A 58-year-old man is going to have chemotherapy for lung cancer. He asks the nurse how the chemotherapeutic drugs will work.The most accurate explanation the nurse can give is which of the following?
"The molecular structure of the DNA is altered."
"Cancer cells are susceptible to drug toxins."
"Chemotherapy encourages cancer cells to divide."
"Chemotherapy affects all rapidly dividing cells."
The Correct Answer is D
Chemotherapy is a treatment modality used to target and destroy rapidly dividing cells, including cancer cells. It works by interfering with the cell division process, which is a characteristic of cancer cells. However, it is important to note that chemotherapy drugs can also affect normal, healthy cells in the body that undergo rapid division, such as cells in the bone marrow, hair follicles, and gastrointestinal lining. This is why chemotherapy can be associated with side effects like bone marrow suppression, hair loss, and gastrointestinal disturbances. While the molecular structure of DNA can be altered by certain chemotherapeutic drugs, this explanation is not comprehensive enough to encompass the overall mechanism of action of chemotherapy.
The statement that "cancer cells are susceptible to drug toxins" is partially true, as cancer cells are generally more vulnerable to the cytotoxic effects of chemotherapy drugs compared to normal cells.
Chemotherapy aims to disrupt the division and growth of cancer cells rather than promoting their division.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is E
Explanation
Dependent edema refers to the accumulation of fluid in the dependent parts of the body, which are areas that are most affected by gravity when a person is in a supine or sitting position for an extended period. The sacrum, which is the triangular bone at the base of the spine, is one such dependent area. It is prone to developing edema when there is increased fluid retention in the body, as seen in the patient's weight gain.
To assess for dependent edema accurately, the nurse can gently press the skin over the sacral area with their fingers and observe the skin turgor or the return of the skin to its normal position after releasing the pressure. If there is edema, the skin may have reduced elasticity and take longer to return to its normal position (poor skin turgor).
While edema can occur in other dependent areas such as the feet, ankles, and lower legs, assessing skin turgor in these areas may not provide an accurate determination of dependent edema as they are located further away from the sacrum and may be influenced by other factors.

Correct Answer is D
Explanation
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of medications commonly used to relieve pain, reduce inflammation, and lower fever. They work by inhibiting the production of prostaglandins, which are substances in the body that play a role in pain and inflammation. Celecoxib specifically belongs to the subclass of NSAIDs known as selective COX-2 inhibitors, which target the enzyme cyclooxygenase-2 (COX-2). By selectively inhibiting COX-2, celecoxib helps to reduce inflammation and pain while potentially minimizing the gastrointestinal side effects associated with traditional non-selective NSAIDs.
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