Why must the nurse instruct a patient receiving metformin (Glucophage XL) to avoid crushing or chewing the medication?

The patient may choke

It would cause blood glucose levels to rise too rapidly.

Irritation of the oral mucosa may occur

The effect of the medication may be changed

Answer and Explanation

The Correct Answer is D

A. The patient may choke: This is not the primary concern for extended-release medications like metformin (Glucophage XL). While choking is a risk with any pill, it's not specific to the need for avoiding crushing or chewing extended-release formulations.
B. It would cause blood glucose levels to rise too rapidly: Crushing or chewing the medication would not cause blood glucose levels to rise rapidly. Instead, it could lead to a more rapid release and absorption of the drug, which might lower blood glucose too quickly, potentially leading to hypoglycemia.
C. Irritation of the oral mucosa may occur: While irritation of the oral mucosa could be a concern with some medications, it is not the primary reason for avoiding the crushing or chewing of extended-release formulations like Glucophage XL.
D. The effect of the medication may be changed: Crushing or chewing an extended-release tablet disrupts its formulation. Glucophage XL is designed to release metformin slowly over time. If the tablet is crushed or chewed, it can result in the entire dose being released at once, which can alter the intended pharmacokinetics and pharmacodynamics of the drug. This could lead to a higher risk of side effects and a loss of the extended-release benefit, ultimately changing the medication's effect and possibly leading to issues like hypoglycemia or gastrointestinal side effects.

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Correct Answer is B

Explanation

A. The patient uses OTC drugs prophylactically: OTC (over-the-counter) medications used appropriately shouldn't directly cause microbial repopulation.
B. The patient stops taking the drug when he or she begins to feel better: This is the most concerning habit. Stopping antibiotics early allows susceptible microbes to survive and multiply, potentially leading to a recurrent infection.
C. The patient switches to multiple drug therapy from single drug therapy: This might be done under a doctor's supervision for complex infections, and wouldn't necessarily promote repopulation.
D. The patient increases the drug dosage when he or she perceives that the therapeutic effect is slowing down: Increasing the dosage without consulting a doctor is not recommended, but it wouldn't necessarily cause repopulation if the original dose was effective.

A. penicillin B. vancomycin C. Streptomycin D. kanamycin (Kantrex)

Correct Answer is B

Explanation

A. Penicillin: Penicillin is ineffective against MRSA because it's resistant to this class of antibiotics.
B. Vancomycin: This is a common antibiotic used to treat MRSA infections.
C. Streptomycin: While used for some bacterial infections, streptomycin is not typically the first choice for MRSA.
D. Kanamycin (Kantrex): Kanamycin can be an option for some MRSA strains, but vancomycin is often preferred

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Why must the nurse instruct a patient receiving metformin (Glucophage XL) to avoid crushing or chewing the medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following common habit of patients may cause microbes to re-populate and re-establish an infection?

Correct Answer is B

Explanation

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Correct Answer is B

Explanation

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Which of the following is important for the nurse to assess and monitor in a patient prescribed metformin (Glucophage)? (Select All that Apply.)