Which of the following heart valves lies between the left atrium and left ventricle and prevents the regurgitation of blood from the ventricle back into the atrium?

As a result of the allergen-antibody reaction, mast cells release histamine.

This is because when mast cells are exposed to an allergen that binds to IgE antibodies attached to their FcɛRI receptors, they release histamine and other inflammatory mediators.

Histamine causes vasodilation, increased capillary permeability, mucus secretion, and smooth muscle contraction, which result in allergic symptoms such as itching, swelling, sneezing, and wheezing.

Mast cells do release histamine in response to allergen-antibody reactions. Some additional sentences are:

Normal ranges of histamine levels vary depending on the tissue and the method of measurement, but they are usually low in healthy individuals and elevated in allergic conditions.

Histamine can be degraded by enzymes such as diamine oxidase and histamine N- methyltransferase, or inhibited by drugs such as antihistamines.

This is because it is an example of a positive feedback loop, which amplifies the change and moves the system away from its normal state.
A negative feedback loop is a mechanism that reverses a deviation from the set point and maintains homeostasis.
Choice A is wrong because increasing heart rate and force of contraction when blood pressure falls is a negative feedback loop that restores blood pressure to normal.
Choice B is wrong because secreting insulin after a meal to return blood sugar concentration toward normal is a negative feedback loop that regulates glucose levels.
Choice D is wrong because shivering when body temperature falls below normal is a negative feedback loop that increases heat production and raises body temperature.
Normal ranges for blood pressure are 90/60 mmHg to 120/80 mmHg, for blood glucose, are 70 mg/dL to 140 mg/dL, and for body temperature are 36.5°C to 37.5°C or 97.7°F to 99.5°F.