Which change occurs first, making patients susceptible to coronary artery disease?
Formation of thrombus in the coronary artery.
Formation of fibrous plaque in the endothelium.
Reduction of blood flow through the coronary arteries.
Development of fatty streaks in the smooth muscles of the endothelium.
The Correct Answer is D
Choice A rationale:
Thrombus formation is a later stage event in coronary artery disease (CAD) and occurs after the development of fatty streaks. Thrombus formation usually happens due to the rupture of atherosclerotic plaques, leading to platelet aggregation and clot formation.
Choice B rationale:
Formation of fibrous plaque in the endothelium is a progression that occurs after the initial development of fatty streaks. Fibrous plaques are formed as a response to the inflammation caused by fatty deposits. They are more stable than fatty streaks but can still lead to narrowing of the arteries.
Choice C rationale:
Reduction of blood flow through the coronary arteries is a consequence of atherosclerosis, which occurs after the initial development of fatty streaks. As the fatty deposits accumulate, they narrow the arteries, leading to reduced blood flow. However, this is not the initial change that makes patients susceptible to CAD.
Choice D rationale:
Development of fatty streaks in the smooth muscles of the endothelium is the initial change that occurs in the development of atherosclerosis, making patients susceptible to coronary artery disease. Fatty streaks are composed of lipid-laden macrophages and smooth muscle cells. Over time, these fatty streaks can progress into fibrous plaques and eventually lead to complications such as thrombus formation and reduced blood flow.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale:
Triple-drug therapy is not the standard treatment for pernicious anemia after a gastrectomy. Pernicious anemia is primarily caused by vitamin B12 deficiency due to the absence of intrinsic factor, which is essential for vitamin B12 absorption.
Choice B rationale:
IV therapy is a broad term and does not specify the treatment for pernicious anemia. In the context of pernicious anemia, cobalamin replacement therapy administered via intramuscular injections is the preferred treatment.
Choice C rationale:
Quadruple-drug therapy is not a recognized treatment for pernicious anemia. The primary treatment for pernicious anemia involves cobalamin replacement therapy to address the vitamin B12 deficiency.
Choice D rationale:
Cobalamin replacement therapy is the appropriate treatment for pernicious anemia after a gastrectomy. Since the patient lacks intrinsic factor, which is necessary for vitamin B12 absorption, cobalamin replacement therapy bypasses the need for intrinsic factor and provides the necessary vitamin B12 directly.
Correct Answer is ["A","D"]
Explanation
Choice A rationale:
Eliminating excess H+ ions (hydrogen ions) is a primary mechanism the kidneys use to buffer acidosis. In acidosis, there is an excess of hydrogen ions in the body, leading to a decrease in pH. The kidneys help regulate the body's pH by excreting hydrogen ions to lower acidity.
Choice B rationale:
Excreting excess water is not a specific acid-base mechanism related to acidosis. While maintaining proper hydration is important for overall health, it does not directly influence the body's acid-base balance in the context of acidosis.
Choice C rationale:
Eliminating excess CO2 is primarily a respiratory mechanism, not a kidney function. CO2 elimination is more related to the lungs' ability to regulate the body's pH by adjusting respiratory rate and depth.
Choice D rationale:
Reabsorbing additional HCO3- ions (bicarbonate ions) is a renal mechanism to buffer acidosis. Bicarbonate ions act as a base and can neutralize excess hydrogen ions, raising the pH of the body fluids.
Choice E rationale:
Reabsorbing additional sodium ions is not a specific acid-base mechanism related to acidosis. While sodium ions are important for various physiological processes, they do not play a direct role in buffering acidosis.
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