When administering an antianginal drug such as nitroglycerin (NTG) the nurse identifies which as the most common response.

Bradycardia

Tachycardia

Hypotension

Dry mouth

Answer and Explanation

The Correct Answer is C

A) Bradycardia
Bradycardia (a slow heart rate) is not the most common response to nitroglycerin (NTG). While NTG can affect heart rate in some individuals, its primary action is related to blood vessels, and it typically leads to vasodilation, which more commonly results in reflex tachycardia (an increased heart rate), rather than bradycardia.

B) Tachycardia
Tachycardia (an increased heart rate) can occur as a compensatory mechanism when nitroglycerin causes vasodilation and a decrease in blood pressure. However, this is more of a secondary effect. The primary action of nitroglycerin is to lower blood pressure (by dilating blood vessels), and in response to the lowered blood pressure, the body may try to compensate by increasing the heart rate.

C) Hypotension
The most common and primary response to nitroglycerin (NTG) administration is hypotension. Nitroglycerin works by relaxing smooth muscle in blood vessels, leading to vasodilation (widening of blood vessels). This reduces the amount of work the heart has to do and lowers the overall blood pressure. Hypotension is expected as part of the therapeutic effect of NTG, especially with a larger dose or rapid administration (e.g., sublingual NTG).

D) Dry mouth
While many medications can cause dry mouth (especially anticholinergic drugs), nitroglycerin is not typically associated with this issue. Its primary action is vasodilation, and while it can cause other symptoms like headaches, dizziness, and hypotension, dry mouth is not considered a common or significant effect.

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Correct Answer is D

Explanation

A) Transdermal patch:
Transdermal patches are designed for slow, continuous delivery of medication through the skin over a long period of time, typically 24 hours. Although they provide steady medication levels, they do not offer a rapid onset of action. This route is more suitable for long-term control of conditions like angina but is not the fastest for immediate relief.

B) Topical ointment:
Topical ointments are applied to the skin and absorb slowly. While they may have local effects, they are not used for quick systemic effects. In the case of nitroglycerin, topical ointments are generally used for sustained release over several hours and are not intended for immediate relief of chest pain.

C) Suspended release:
Suspended release formulations are designed to release the drug slowly over time. Like transdermal patches, these formulations are meant for long-term management, not for rapid onset. A suspended release formulation of nitroglycerin would not provide the immediate relief that is typically needed in cases of acute angina or chest pain.

D) Sublingual:
The sublingual route provides the most rapid onset of action for nitroglycerin. When nitroglycerin is placed under the tongue, it is absorbed directly into the bloodstream through the mucous membranes of the mouth. This bypasses the digestive system and the liver (first-pass metabolism), allowing the drug to take effect quickly—usually within 1 to 3 minutes—making it ideal for acute relief of chest pain or angina. This route is commonly used for emergencies when rapid relief is needed.

A. 3 mL B. 2 mL C. 4 mL D. 6 mL

Correct Answer is C

Explanation

Let's calculate the dosage using the provided information.

Information from the label:

Bumetanide concentration: 0.25 mg/mL

Available volume: 10 mL vial

Order: Bumex (bumetanide) 1 mg IV daily

Calculation:

Determine the desired dose: 1 mg

Use the formula:

Desired dose (mg) / Available concentration (mg/mL) = Volume to administer (mL)

Substitute the values:

1 mg / 0.25 mg/mL = Volume to administer (mL)

Calculate:

Volume to administer = 4 mL

Therefore, the correct answer is C. 4 mL

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When administering an antianginal drug such as nitroglycerin (NTG) the nurse identifies which as the most common response.

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Naxlex Comprehensive Predictor Exams

A nurse is reinforcing teaching with a group of nurses about the administration of nitroglycerin. Which of the following routes of administration provides the most rapid onset for the client?

Correct Answer is D

Explanation

Calculate the dosage using the label below. Round to the nearest tenth place. Order: Bumex (bumetanide) 1 mg IV daily Available:

Correct Answer is C

Explanation

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