What is the term used for a well understood drug model with which other drugs in its representative class are compared?

Antibiotics

Pharmacologic Drug

Prototype Drug

Therapeutic Drug

Answer and Explanation

The Correct Answer is C

Choice A reason: This is incorrect. Antibiotics are not a term for a drug model, but a class of drugs that are used to treat bacterial infections. Antibiotics can have different chemical structures, mechanisms of action, and modes of action. For example, penicillin is a prototype drug of the beta lactam antibiotics, which inhibit the synthesis of bacterial cell walls¹.

Choice B reason: This is incorrect. Pharmacologic drug is not a term for a drug model, but a general term for any substance that has a physiological effect on the body. Pharmacologic drugs can belong to different classes, such as analgesics, antihistamines, or antivirals. For example, aspirin is a prototype drug of the nonsteroidal anti-inflammatory drugs (NSAIDs), which reduce pain, inflammation, and fever.

Choice C reason: This is correct. Prototype drug is the term used for a well understood drug model with which other drugs in its representative class are compared. A prototype drug is an individual drug that has similar chemical structure, mechanism of action, and mode of action as other drugs in its class. A prototype drug is often the first developed or the most important drug in its class, and is used as a reference for comparison. For example, morphine is a prototype drug of the opioid analgesics, which relieve pain by binding to opioid receptors in the brain and spinal cord.

Choice D reason: This is incorrect. Therapeutic drug is not a term for a drug model, but a term for any drug that is used to treat or prevent a disease or disorder. Therapeutic drugs can belong to different classes, such as antibiotics, antihypertensives, or antidepressants. For example, metformin is a prototype drug of the biguanide antidiabetic drugs, which lower blood glucose levels by reducing glucose production in the liver and increasing glucose uptake in the muscles.

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Correct Answer is A

Explanation

Choice A reason: Relief of heartburn is the correct outcome that indicates that famotidine is therapeutic. Famotidine is a medication that belongs to the class of H2 receptor antagonists, which work by blocking the action of histamine on the H2 receptors of the stomach cells, thereby reducing the production of gastric acid. Famotidine is used to treat and prevent conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and Zollinger Ellison syndrome, which are characterized by excessive acid secretion and irritation of the esophagus and stomach. Famotidine can relieve the symptoms of heartburn, which is a burning sensation in the chest or throat caused by the reflux of stomach acid into the esophagus.

Choice B reason: Cessation of diarrhea is not an outcome that indicates that famotidine is therapeutic. Famotidine is a medication that belongs to the class of H2 receptor antagonists, which work by blocking the action of histamine on the H2 receptors of the stomach cells, thereby reducing the production of gastric acid. Famotidine does not affect the motility or secretion of the intestines, and it is not used to treat diarrhea, which is a condition of frequent and loose bowel movements. Diarrhea can have various causes, such as infections, medications, food intolerance, or inflammatory bowel disease, and it requires different treatments depending on the underlying cause. Famotidine is not effective for treating diarrhea, and it may even worsen it by reducing the acidity of the stomach and increasing the risk of bacterial overgrowth.

Choice C reason: Passage of flatus is not an outcome that indicates that famotidine is therapeutic. Famotidine is a medication that belongs to the class of H2 receptor antagonists, which work by blocking the action of histamine on the H2 receptors of the stomach cells, thereby reducing the production of gastric acid. Famotidine does not affect the digestion or fermentation of food in the gastrointestinal tract, and it is not used to treat flatulence, which is the accumulation and expulsion of gas from the stomach or intestines. Flatulence can have various causes, such as swallowing air, eating certain foods, or having a bacterial imbalance in the gut, and it requires different treatments depending on the underlying cause. Famotidine is not effective for treating flatulence, and it may even increase it by reducing the acidity of the stomach and altering the gut flora.

Choice D reason: Absence of constipation is not an outcome that indicates that famotidine is therapeutic. Famotidine is a medication that belongs to the class of H2 receptor antagonists, which work by blocking the action of histamine on the H2 receptors of the stomach cells, thereby reducing the production of gastric acid. Famotidine does not affect the motility or secretion of the intestines, and it is not used to treat constipation, which is a condition of infrequent or difficult bowel movements. Constipation can have various causes, such as dehydration, lack of fiber, medications, or bowel obstruction, and it requires different treatments depending on the underlying cause. Famotidine is not effective for treating constipation, and it may even cause it by reducing the acidity of the stomach and slowing down the digestion.

A. I will not engage in strenuous activity after taking Fluticasone. B. I will eat potassium rich foods now. C. I should watch for signs and symptoms of hyperglycemia. D. I will not eat for 4 hours after taking Fluticasone.

Correct Answer is C

Explanation

Choice A reason: This is incorrect. Fluticasone is a corticosteroid that is used to treat asthma and allergic rhinitis. It does not affect the patient's ability to exercise or engage in strenuous activity. In fact, exercise can help improve lung function and reduce inflammation.

Choice B reason: This is incorrect. Fluticasone does not affect the patient's potassium levels. Potassium is an electrolyte that is important for the function of the heart, muscles, and nerves. Some medications, such as diuretics, can lower potassium levels and require the patient to eat potassium rich foods, such as bananas, potatoes, and tomatoes. Fluticasone is not one of them.

Choice C reason: This is correct. Fluticasone can cause hyperglycemia, which is high blood sugar. This can occur because corticosteroids can increase the production of glucose in the liver and reduce the sensitivity of the cells to insulin, the hormone that regulates blood sugar. Hyperglycemia can cause symptoms such as increased thirst, hunger, urination, fatigue, and blurred vision. The patient should monitor their blood sugar levels regularly and report any changes to their doctor.

Choice D reason: This is incorrect. Fluticasone does not affect the patient's digestion or appetite. It can be taken with or without food. There is no need to avoid eating for 4 hours after taking Fluticasone. However, the patient should rinse their mouth with water after using Fluticasone inhaler or nasal spray, as this can help prevent oral thrush, a fungal infection that can cause white patches, soreness, and bleeding in the mouth.

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What is the term used for a well understood drug model with which other drugs in its representative class are compared?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is taking a health history of a client who reports occasionally taking several over-the-counter medications, including an H2 receptor antagonist (famotidine). Which of the following outcomes indicates that famotidine is therapeutic?

Correct Answer is A

Explanation

The nurse is teaching a patient about the long-term use of Fluticasone. The patient demonstrates understanding when they state:

Correct Answer is C

Explanation

A nurse is preparing to administer atropine to a patient with symptomatic bradycardia. Which of the following is the primary therapeutic effect of atropine in this scenario?

A nurse is caring for a client who is prescribed diphenhydramine to relieve pruritus. The client asks the nurse how he can minimize the daytime sedation he is experiencing. Which of the following responses should the nurse give?

Escitalopram (Lexapro) belongs to which class of medications?

Which phase of pharmacokinetics involves the movement of a drug from its site of administration to the bloodstream?

A nurse is completing a medication history for a client who reports using over-the-counter calcium carbonate antacid. Which of the following recommendations should the nurse make about taking this medication?

A nurse is preparing to administer phenylephrine as a vasopressor to treat a patient for hypotension. The desired therapeutic effect of phenylephrine in this context is:

A nurse is providing discharge teaching to a client who has asthma and new prescriptions for Albuterol and Atrovent, both by nebulizer. Which of the following statements by the client indicates an understanding of the teaching?

The nurse is teaching a patient who has been diagnosed with a gastric ulcer and has been prescribed an antacid. The patient demonstrates understanding when they state: