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route of administration quickly delivers medication directly to their sites of action.

A. Inhale rapidly when using the spacer with the MDI. Inhalation should be slow and deep to allow the medication to be delivered effectively to the lungs. Rapid inhalation can cause the medication to be deposited in the oropharynx instead.
B. The spacer increases the amount of medication delivered to the lungs. A spacer helps to improve medication delivery to the lungs by allowing more time for the medication to be inhaled and reducing deposition in the mouth and throat.
C. The spacer increases the amount of medication delivered to the oropharynx. The spacer actually reduces the amount of medication delivered to the oropharynx by holding the medication in a chamber, allowing for more medication to reach the lungs.
D. Cover exhalation slots of the spacer with lips when inhaling. The exhalation slots should remain open to allow for normal breathing. The child should create a good seal around the mouthpiece but not block any slots.

A. Antacids: Antacids are generally used to neutralize stomach acid and can provide symptomatic relief for peptic ulcer disease (PUD). They are not typically contraindicated and can be part of the treatment regimen, although they do not address the underlying cause of PUD.
B. NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to irritate the gastric mucosa and can exacerbate or cause peptic ulcers by inhibiting the production of protective prostaglandins in the stomach lining. Patients with peptic ulcer disease should avoid NSAIDs to prevent further irritation and ulcer formation.
C. PPIs: Proton pump inhibitors (PPIs) are commonly prescribed to reduce gastric acid secretion and promote ulcer healing in peptic ulcer disease. They are a key component of the treatment regimen and not to be avoided unless there are specific contraindications.
D. H2-receptor blockers: H2-receptor blockers reduce stomach acid production and are used to treat and prevent peptic ulcers. They are an important part of the management strategy for PUD and are not typically contraindicated.