The nurse is teaching a patient with type 2 diabetes about intermediate-acting insulin (NPH). Which of the following statements by the patient indicates a need for further teaching?

A. "There can be an unsafe reaction between your antidepressant and St. John's wort, which is why taking them both is discouraged." is correct; St. John's wort can reduce the effectiveness of SSRIs and may increase the risk of serotonin syndrome, making it vital for the nurse to address this safety concern.

B. "Herbal remedies often contain unknown doses of the desired ingredient, which can be dangerous." is a valid point, but it does not specifically address the interaction with the client’s current medication.

C. "It's very important that you not take the St. John's wort at the same time of day as your antidepressant." is misleading; the concern is not just about timing but about taking both together at all.

D. "It's very important that you comply with your prescribed treatment." while true, this response does not directly address the specific risks associated with combining St. John's wort and citalopram.

A. Spironolactone is a potassium-sparing diuretic, meaning it helps retain potassium while promoting sodium and water excretion. This makes it advantageous for clients who may be at risk for hypokalemia with furosemide, which can lead to significant potassium loss.

B. This statement is incorrect; spironolactone causes less potassium loss compared to furosemide, making it a better option for those needing to maintain potassium levels.

C. This statement is misleading; spironolactone does promote diuresis but does not cause greater water losses than furosemide.

D. This is incorrect; while spironolactone does promote sodium excretion, it does not do so to a greater extent than furosemide, which is a more potent diuretic.