The nurse is providing discharge instructions to a patient who has a prescription for phenytoin. Which of the following information should the nurse include?

Choice A rationale:
Losing 2 pounds in 2 weeks is not a significant weight loss and may not be a cause for concern in this context. It's important to monitor weight trends over time, but this isolated statement doesn't necessarily require immediate discussion.
Choice B rationale:

Engaging in physical activity like swimming is generally beneficial for individuals with rheumatoid arthritis. It can help improve joint mobility, reduce pain, and enhance overall well-being. The nurse might encourage the client to discuss any specific concerns or limitations with their healthcare provider, but the activity itself is not alarming.
Choice C rationale:
Taking an antibiotic concurrently with naproxen can potentially increase the risk of adverse effects. Some antibiotics, like those in the fluoroquinolone class (e.g., ciprofloxacin, levofloxacin), can interact with naproxen and increase the risk of tendonitis or tendon rupture. This interaction warrants further discussion to ensure the client is aware of potential risks and to explore alternative medications if necessary.
Choice D rationale:
Using applesauce to facilitate medication intake is a common and acceptable practice. It does not affect the absorption or efficacy of naproxen.

Choice A rationale:
History of rheumatologic conditions: Research has demonstrated a link between fibromyalgia and other rheumatologic conditions, such as rheumatoid arthritis, lupus, and osteoarthritis. Individuals with these conditions may have a predisposition to developing fibromyalgia due to shared genetic factors, immune system dysregulation, and chronic inflammation.
Choice B rationale:
Nutritional deficiency: While nutritional deficiencies, particularly in vitamin D, magnesium, and iron, have been associated with fibromyalgia symptoms, there's not enough evidence to establish them as direct risk factors for its development.
Nutritional deficiencies can worsen pain and fatigue, but they aren't considered primary causes of fibromyalgia.
Choice C rationale:

Previous injury to the bone: Past bone injuries typically aren't considered a risk factor for fibromyalgia. Fibromyalgia is a chronic pain syndrome that affects muscles and soft tissues, not bones themselves. While pain from an injury might trigger fibromyalgia symptoms, it's not a direct cause.
Choice D rationale:
Deep sleep deprivation: Sleep disturbances, especially disruptions in deep sleep (also known as slow-wave sleep), are strongly linked to fibromyalgia. Deep sleep is crucial for restorative processes in the body, including pain regulation. Insufficient deep sleep can lead to heightened pain sensitivity and contribute to the development of fibromyalgia.
Choice E rationale:
Physical and emotional trauma: Physical and emotional trauma, such as experiencing accidents, abuse, or significant psychological stress, can significantly increase the risk of developing fibromyalgia. Trauma can trigger changes in the brain's pain processing pathways and stress hormone regulation, contributing to chronic pain and other fibromyalgia symptoms.