The nurse is caring for a patient who has multiple sclerosis. The patient is experiencing an acute attack. Which drug does the nurse anticipate the provider will order?

Interferon-B (IFN-B)

Mitoxantrone

Glatiramer acetate (Copaxone)

Methylprednisolone (Solu-Medrol)

Answer and Explanation

The Correct Answer is D

A) Interferon-B (IFN-B): Interferon-beta is a disease-modifying therapy (DMT) used for multiple sclerosis (MS) to reduce the frequency and severity of attacks and slow disease progression. However, it is not typically used during an acute exacerbation of MS. It is more commonly prescribed for long-term management of the disease.
B) Mitoxantrone: Mitoxantrone is an immunosuppressive agent that is used as a disease-modifying therapy for patients with more aggressive forms of MS. While it can be helpful in reducing the frequency of attacks, it is not the first-line treatment during an acute relapse. Mitoxantrone is often considered for long-term use when other therapies are not effective.
C) Glatiramer acetate (Copaxone): Glatiramer acetate is another disease-modifying therapy for MS. It works by altering the immune response to protect the myelin sheath. Like interferon-beta, it is used for long-term management, not for acute attacks. It is not typically used during an exacerbation of MS.
D) Methylprednisolone (Solu-Medrol): Methylprednisolone, a corticosteroid, is the standard treatment for acute exacerbations of multiple sclerosis. It works by reducing inflammation, which helps to decrease the severity of symptoms during an MS relapse. The nurse would anticipate this drug being prescribed to manage the acute inflammatory episode and speed recovery from the attack. This medication is often administered intravenously in high doses and then tapered as the patient stabilizes.

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Correct Answer is C

Explanation

A) Increased calcium: Sympathetic activation typically does not cause a direct increase in calcium levels. Calcium levels are more influenced by factors like parathyroid hormone (PTH) and vitamin D, or conditions such as bone disease or renal issues. Although some stress responses can lead to changes in calcium metabolism, an increase in calcium is not a typical response to sympathetic activation.

B) Decreased sodium: While sodium imbalances can occur in various conditions, the sympathetic nervous system does not directly cause a decrease in sodium. The body's handling of sodium is more influenced by factors like kidney function and the renin-angiotensin-aldosterone system. Stress-related changes in sodium levels are less likely to cause a significant decrease in sodium, making this an unlikely focus in monitoring.

C) Decreased potassium: During stress, the body releases catecholamines (like epinephrine) as part of the sympathetic nervous response, which stimulates the movement of potassium into cells. This can result in a transient decrease in serum potassium levels (hypokalemia). Monitoring for decreased potassium is important, as low potassium can lead to cardiac arrhythmias and muscle weakness, which are particularly concerning after surgery or trauma.

D) Increased chloride: Chloride is typically maintained in balance with sodium, and while it may shift in certain conditions, sympathetic activation does not directly lead to increased chloride levels. Most chloride imbalances are secondary to changes in sodium, acid-base disturbances, or kidney function. Therefore, an increase in chloride is less likely in this scenario.

A. A patient with hypotension B. A patient with a concussion C. A patient 3 days after surgery D. A patient with cancer

Correct Answer is D

Explanation

A) A patient with hypotension:
Patients with hypotension may have reduced blood flow to organs, which could potentially decrease the absorption and effectiveness of many medications, including opioids. As a result, the need for a higher dose is not typical. Instead, careful dosing and monitoring are required to avoid further lowering blood pressure, which could lead to more complications.

B) A patient with a concussion:
Concussions affect the brain and can lead to symptoms like dizziness, confusion, or nausea, which may alter how medications are metabolized or tolerated. However, a concussion does not typically require higher opioid doses. In fact, opioids should be used cautiously in such patients due to the risk of exacerbating neurological symptoms or respiratory depression.

C) A patient 3 days after surgery:
Patients recovering from surgery may require pain management, but the opioid dose typically adjusts based on their pain levels and recovery stage. While some patients may still need opioids for pain control, they may not require higher-than-expected doses. Over time, doses are often tapered as healing progresses, and pain lessens.

D) A patient with cancer:
Cancer patients, particularly those with advanced stages or chronic pain, may develop increased opioid tolerance. This means that over time, they may require higher doses to achieve the same level of pain relief. This phenomenon is known as "opioid tolerance," where the body becomes less responsive to the drug, necessitating dose adjustments.

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The nurse is caring for a patient who has multiple sclerosis. The patient is experiencing an acute attack. Which drug does the nurse anticipate the provider will order?

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Naxlex Comprehensive Predictor Exams

Correct Answer is C

Explanation

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