The nurse is asked by a client to explain the differences and similarities between methadone and buprenorphine for treatment of opioid use disorder. The nurse's best response is

Choice A rationale: Donepezil works by enhancing the action of acetylcholine, improving neuronal transmission, so this statement is accurate.
Choice B rationale: Upset stomach is a common side effect of donepezil, and the patient's awareness of this potential side effect indicates understanding.
Choice C rationale: Taking donepezil with food can reduce the risk of stomach upset, so this statement is appropriate.
Choice D rationale: Donepezil helps manage symptoms of Alzheimer's Disease but does not stop the progression or damage to neurons. Further education is needed on the realistic expectations of the medication.

Choice A rationale: Dry mouth is a known side effect of clonidine, and denying this information would be inaccurate.
Choice B rationale: Providing strategies to alleviate the side effect, such as offering hard candy or gum, is a proactive approach to managing the dry mouth without discontinuing the medication.
Choice C rationale: Stopping antihypertensive medication abruptly can lead to rebound hypertension, and the nurse should not encourage discontinuation without consulting the healthcare provider.
Choice D rationale: Adjusting the dose of clonidine should be done under the guidance of a healthcare provider; self-adjustment without professional input is not advisable.