The client with gout is prescribed allopurinol. Dosing will be adjusted based on
Target serum drug levels
Absence of Gl effects
Serum creatinine
Plasma urate level
The Correct Answer is D
Choice A rationale: Allopurinol dosing is not typically adjusted based on target serum drug levels.
Choice B rationale: The absence of gastrointestinal (GI) effects is not a parameter used to adjust the dosing of allopurinol.
Choice C rationale: This is partially correct. Allopurinol dosing is adjusted based on renal function, but specifically, it is adjusted based on serum creatinine levels. The higher the creatinine levels, the lower the dose of allopurinol should be.
Choice D rationale: This is correct. Allopurinol dosing is adjusted based on plasma urate levels. The goal is to reduce uric acid levels in the blood to prevent the formation of urate crystals and subsequent gout attacks. Regular monitoring of plasma urate levels helps determine the effectiveness of the medication, and adjustments can be made to achieve the target urate level.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale: Decreased strength is not the desired effect of baclofen.
Baclofen is a muscle relaxant and is expected to improve muscle tone rather than decrease strength.
Choice B rationale: Baclofen is used to suppress spasticity, which is a common symptom in patients with multiple sclerosis.
Choice C rationale: Improved muscle tone is the desired effect of baclofen, making this the correct choice.
Choice D rationale: Increased muscle resistance is not the desired effect of baclofen.
Correct Answer is A
Explanation
Choice A rationale: Prednisone can potentiate the effects of beta-blockers like metoprolol, and dose adjustments may be necessary to avoid excessive bradycardia.
Choice B rationale: Acetaminophen is not typically affected by prednisone in a way that requires dose adjustment.
Choice C rationale: Lisinopril is not typically affected by prednisone in a way that requires dose adjustment.
Choice D rationale: Insulin may need adjustment due to the hyperglycemic effects of prednisone.
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