The nurse administers a drug that stimulate the parasympathetic nervous system. What physiologic response would indicate that the drug is working?

Pupil dilation

Increased gastrointestinal motility

Vasoconstriction

Increased heart rate

Answer and Explanation

The Correct Answer is B

A) Pupil dilation:
Pupil dilation is typically a response from stimulation of the sympathetic nervous system, not the parasympathetic system. The parasympathetic system tends to cause pupil constriction, so pupil dilation would not be an expected response to a parasympathetic agonist.

B) Increased gastrointestinal motility:
Stimulation of the parasympathetic nervous system, which is responsible for the "rest and digest" response, promotes the movement of food through the digestive tract, increasing gastrointestinal motility. This response is a classic sign that the parasympathetic system is being activated. Drugs that stimulate the parasympathetic nervous system often aim to enhance digestive functions.

C) Vasoconstriction:
Vasoconstriction is typically mediated by the sympathetic nervous system, not the parasympathetic system. The sympathetic nervous system activates alpha-adrenergic receptors that cause blood vessels to constrict, raising blood pressure. The parasympathetic system, on the other hand, typically promotes vasodilation, lowering blood pressure.

D) Increased heart rate:
Increased heart rate is generally associated with the sympathetic nervous system, which prepares the body for "fight or flight." The parasympathetic nervous system, in contrast, slows down the heart rate through vagal stimulation, so an increase in heart rate would not be the expected response to parasympathetic stimulation.

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Correct Answer is D

Explanation

A) Phagocytosis: Phagocytosis refers to the process by which a cell engulfs large particles, such as pathogens or debris, and brings them into the cell. It is not related to the movement of hormones across the cell membrane.
B) Endocytosis: Endocytosis is the process where a cell engulfs substances from the external environment and brings them into the cell. However, this term is typically used when substances like nutrients or larger molecules are taken into the cell, not when hormones are being secreted out of the cell.
C) Pinocytosis: Pinocytosis is a type of endocytosis in which the cell engulfs extracellular fluid and dissolved substances. It is often referred to as "cell drinking" and involves the uptake of fluids, not the secretion of hormones across the membrane.
D) Exocytosis: This is the correct answer. Exocytosis is the process by which substances, such as hormones or neurotransmitters, are transported from inside the cell to the outside by vesicles that fuse with the cell membrane. In the case of hormones, they are synthesized within the cell and then released into the extracellular space via exocytosis, enabling them to reach their target sites.

A. Norepinephrine, dopamine, and serotonin B. Epinephrine, Norepinephrine, and Acetylcholine C. Acetylcholine, gamma-aminobutyric acid, and serotonin D. gamma-aminobutyric acid, dopamine, and epinephrine

Correct Answer is A

Explanation

A) Norepinephrine, dopamine, and serotonin:
Depression has been strongly linked to deficiencies in certain neurotransmitters in the brain, specifically norepinephrine, dopamine, and serotonin. These neurotransmitters play significant roles in regulating mood, emotions, and behavior. When their levels are low, individuals may experience symptoms of depression, such as sadness, low energy, anhedonia (inability to feel pleasure), and difficulty concentrating. Antidepressant medications often work by increasing the availability of these neurotransmitters in the brain.

B) Epinephrine, Norepinephrine, and Acetylcholine:
While norepinephrine plays a key role in depression, epinephrine and acetylcholine are not typically highlighted as the primary neurotransmitters involved in depression. Epinephrine (also known as adrenaline) is more associated with the body’s stress response and fight-or-flight reaction. Acetylcholine is involved in memory and learning processes, but it is not the primary neurotransmitter related to depression.

C) Acetylcholine, gamma-aminobutyric acid, and serotonin:
Acetylcholine and gamma-aminobutyric acid (GABA) are involved in many brain functions, but they are not the primary neurotransmitters linked to depression. While GABA may play a role in mood regulation, it is not typically associated with depression in the same way that serotonin, norepinephrine, and dopamine are. Serotonin is the exception in this answer

D) Gamma-aminobutyric acid, dopamine, and epinephrine:
Although dopamine is involved in depression, gamma-aminobutyric acid (GABA) and epinephrine are not the key neurotransmitters associated with the pathophysiology of depression. Epinephrine primarily affects the stress response, and while GABA does influence mood and anxiety, it is not the main neurotransmitter linked to depression itself.

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The nurse administers a drug that stimulate the parasympathetic nervous system. What physiologic response would indicate that the drug is working?

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