The healthcare provider prescribes propylthiouracil (PTU) and Lugol’s solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?

Schedule both medications at bedtime.

Administer iodine one hour before PTU.

Give parental dose once every 24 hours.

Offer both drugs together with a meal.

Answer and Explanation

The Correct Answer is B

A) Schedule both medications at bedtime:
Administering both medications at bedtime may not be the most appropriate schedule. PTU is typically administered multiple times a day to maintain consistent therapeutic levels in the bloodstream. Additionally, administering Lugol’s solution at bedtime may not provide sufficient time for the iodine to take effect before the PTU.

B) Administer iodine one hour before PTU:
This option is correct. Lugol’s solution, a strong iodine solution, is often given before antithyroid medications such as PTU or methimazole to temporarily block thyroid hormone production. Administering iodine about one hour before PTU allows the iodine to be taken up by the thyroid gland, effectively reducing thyroid hormone synthesis before the PTU starts to inhibit the conversion of T4 to T3.

C) Give parental dose once every 24 hours:
This option does not address the timing of administration between PTU and Lugol’s solution. While it may be correct for the dosing frequency of PTU, it does not specify when to administer Lugol’s solution in relation to PTU.

D) Offer both drugs together with a meal:
Administering both drugs together with a meal may not be appropriate, especially considering that Lugol’s solution needs to be absorbed into the bloodstream to exert its effect on the thyroid gland. Administering Lugol’s solution and PTU together may not allow adequate time for the iodine to take effect before the PTU starts to inhibit thyroid hormone production.

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Correct Answer is B

Explanation

A) Colorectal cancer:
While a history of colorectal cancer is important to note in a client’s medical history, it is not typically a contraindication for estrogen replacement therapy. Estrogen replacement therapy may even have benefits in terms of reducing the risk of colorectal cancer in some cases. However, the primary concern in this scenario is the client’s history of pulmonary embolism, which presents a significant risk factor for adverse outcomes with estrogen therapy.

B) Pulmonary embolism:

A history of pulmonary embolism is a significant contraindication for estrogen replacement therapy. Estrogen therapy increases the risk of thromboembolic events, and individuals with a history of pulmonary embolism are already predisposed to such events. Administering estrogen replacement therapy to a client with a history of pulmonary embolism could further increase the risk of recurrent embolism or deep vein thrombosis, leading to potentially life-threatening complications.

C) Dyspareunia:

Dyspareunia, or painful sexual intercourse, is a symptom commonly associated with menopause and may be an indication for estrogen replacement therapy. However, it is not a contraindication for treatment unless there are other complicating factors that need to be considered.

D) Osteoporosis:

Osteoporosis, characterized by decreased bone density and increased susceptibility to fractures, is often treated with estrogen replacement therapy to help maintain bone health and reduce the risk of fractures. While it is important to consider the client’s osteoporosis diagnosis when initiating estrogen therapy, it is not typically a contraindication for treatment unless there are other specific concerns or complications present.

A. When using the discus, have the client breathe out rapidly into the mouthpiece. B. Explain that the client should not use the discus more than twice daily. C. Offer the discus to the client for use during an acute asthma attack. D. Clients using the discus may experience decreased blood pressure.

Correct Answer is B

Explanation

A) When using the discus, have the client breathe out rapidly into the mouthpiece: This instruction is incorrect because with dry powder inhalers (DPIs) like the fluticasone propionate and salmeterol discus, clients should exhale slowly and completely before inhaling the medication. Breathing out rapidly may cause the medication to be dispersed ineffectively, reducing its therapeutic benefit. By exhaling slowly, clients ensure better delivery of the medication to their lungs, maximizing its effectiveness in controlling asthma symptoms.
B) Explain that the client should not use the discus more than twice daily: This is the correct answer. Fluticasone propionate and salmeterol combination inhalers are typically used on a scheduled basis to maintain asthma control. Overuse of these medications can lead to increased risk of side effects, such as oral thrush or hoarseness from the steroid component (fluticasone propionate), or increased heart rate from the long-acting beta agonist (salmeterol). Moreover, exceeding the prescribed dose may not provide additional benefits in controlling asthma symptoms and can indicate inadequate control, necessitating a review of the treatment plan by the healthcare provider.
C) Offer the discus to the client for use during an acute asthma attack: Using a combination inhaler during an acute asthma attack is not appropriate. During acute exacerbations, clients should use short-acting bronchodilators (e.g., albuterol) for quick relief of symptoms. Combination inhalers like fluticasone propionate and salmeterol are intended for long-term maintenance therapy to prevent asthma symptoms, not for acute symptom relief.
D) Clients using the discus may experience decreased blood pressure: This statement is incorrect. Fluticasone propionate and salmeterol combination inhalers are not known to cause decreased blood pressure as a side effect. However, salmeterol, being a long-acting beta agonist, can potentially cause an increase in heart rate, especially when used excessively, but this is not related to blood pressure changes. It's essential to focus on the appropriate use and dosing schedule of the medication to achieve optimal asthma control and minimize adverse effects.

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The healthcare provider prescribes propylthiouracil (PTU) and Lugol’s solution, a strong iodine solution, for a client with hyperthyroidism. How should the nurse schedule the administration of these medications?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client who is experiencing vasomotor symptoms related to menopause receives a new prescription for estrogen replacement. Which client condition should the nurse report the healthcare provider prior to administering the first dose of the medication?

Correct Answer is B

Explanation

To control asthma, a client in a residential treatment facility uses a fluticasone propionate and salmeterol discus inhalation system, which provides an inhaled powdered form of these combined medications. Which instruction should the nurse provide to this client's caregivers?

Correct Answer is B

Explanation

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