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The healthcare provider prescribes cefazolin 800 mg IM every 6 hours. The available vial is labeled, "Cefazolin 1 gram," and the instructions for reconstitution state, "For IM use, add 2.5 mL sterile water for injection to provide a total volume of 3.0 mL How many mL should the nurse administer? (Enter numerical value only. If rounding is required, round to the nearest tenth.)
Answer and Explanation

The Correct Answer is ["2.4"]

Here's how to calculate the volume (mL) the nurse should administer for cefazolin:

1. We know the following:

Prescribed dose: 800 mg cefazolin IM every 6 hours (given)

Vial content: 1 gram cefazolin (given)

However, we need to consider the reconstitution process for accurate dosage calculation.

Reconstitution information:

For IM use, add 2.5 mL sterile water for injection.

This dilution creates a total volume of 3.0 mL.

3. We need to find the concentration of cefazolin in the reconstituted solution (mg/mL).

Concentration (mg/mL) = Total drug amount (mg) / Total volume (mL) after reconstitution

Concentration (mg/mL) = 1 gram (which is 1000 mg) / 3.0 mL

Concentration (mg/mL) = 333.33 mg/mL (round to nearest tenth)

4. Now, we can find the volume to administer for the prescribed dose (800 mg) considering the concentration (333.33 mg/mL) in the reconstituted solution.

Volume to administer (mL): Dose (mg) / Concentration (mg/mL)

Volume to administer (mL): 800 mg / 333.33 mg/mL

Volume to administer (mL): 2.40 mL (round to nearest tenth)

Therefore, the nurse should administer approximately 2.4 mL of the reconstituted cefazolin solution intramuscularly.


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Related Questions

Correct Answer is ["4.7"]

Explanation

Here's how to calculate the volume (mL) of the reconstituted ampicillin solution the nurse should administer for each dose:

1. We know the following:

Prescribed dose: 140 mg ampicillin (given)

Vial information:

Contains 250 mg ampicillin powder (given)

Reconstituted with 8.3 mL sterile normal saline (given)

Yields a final concentration of 30 mg/mL (given)

2. We need to find the volume (mL) of the reconstituted solution containing the prescribed dose (140 mg) considering the final concentration (30 mg/mL).

Steps:

a. Don't consider the initial volume (8.3 mL) of sterile normal saline. The final concentration (30 mg/mL) refers to the concentration in the diluted solution after adding the saline.

b. Use the following formula:

Volume to administer (mL) = Dose (mg) / Concentration (mg/mL)

c. Plug in the values:

Volume to administer (mL) = 140 mg / 30 mg/mL

Volume to administer (mL) = 4.67 mL (round to nearest tenth)

Therefore, the nurse should administer approximately 4.7 mL of the reconstituted ampicillin solution intravenously every 8 hours for the child.

Correct Answer is ["440"]

Explanation

The pharmacy provides a 110 mL premixed solution of pantoprazole to be infused over 15 minutes.

First, let’s find out how many mL should be delivered per minute.

We divide the total volume by the total time in minutes:

RateinmL/min = 110mL /15min ​≈ 7.33mL/min

We need to convert this to mL/hr since we want the rate in mL/hr.

There are 60 minutes in an hour, so:

RateinmL/hr = 7.33mL/min×60 = 440mL/hr

So, the nurse should program the secondary infusion to deliver 440 mL/hr.

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