A child with growth failure is receiving somatropin (rDNA origin) 1.25 mg subcutaneously (subQ) daily. The nurse reconstitutes the vial with 5 mL of bacteriostatic water for injection to yield a solution concentration of 5 mg/mL. How many mL should the nurse administer? (Enter numeric value only. If rounding is required, round to the nearest hundredth.)
The Correct Answer is ["0.25"]
Here's how to calculate the volume (mL) the nurse should administer for somatropin:
1. We know the following:
Prescribed dose: 1.25 mg somatropin (given)
Concentration after reconstitution: 5 mg/mL (given)
2. We need to find the volume (mL) to administer for the prescribed dose (1.25 mg) considering the concentration (5 mg/mL) of the reconstituted solution.
Volume to administer (mL): Dose (mg) / Concentration (mg/mL)
Volume to administer (mL): 1.25 mg / 5 mg/mL
Volume to administer (mL) = 0.25 mL (round to nearest hundredth)
Therefore, the nurse should administer 0.25 mL of the reconstituted somatropin solution subcutaneously.
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Related Questions
Correct Answer is ["1.3"]
Explanation
Here's how to calculate the volume (mL) of filgrastim the nurse should administer:
Client weight conversion:
Client weight: 176 pounds
Since medication dosage is based on weight per kilogram (kg), we need to convert the weight to kg for accurate calculation.
Conversion factor: 1 kg = 2.205 lbs
Client weight (kg) = 176 pounds / 2.205 lbs/kg
Client weight (kg) = 80 kg (round to nearest whole number)
Filgrastim dose per kg:
Dose per kg = 5 mcg/kg (given)
Filgrastim concentration:
The medication vial is labeled 300 mcg/mL. This indicates there are 300 mcg of filgrastim in every 1 mL of solution.
We need to find the volume (mL) containing the prescribed dose (based on weight) of filgrastim (5 mcg/kg) considering the concentration (300 mcg/mL) in the vial.
Total filgrastim dose (mcg): Dose (mcg/kg) x Client weight (kg)
Total filgrastim dose (mcg): 5 mcg/kg * 80 kg
Total filgrastim dose (mcg): 400 mcg
Volume to administer (mL): Total dose (mcg) / Concentration (mcg/mL)
Volume to administer (mL): 400 mcg / 300 mcg/mL
Volume to administer (mL) = 1.33 mL (round to nearest tenth)
Therefore, the nurse should administer approximately 1.3 mL of filgrastim subcutaneously.
Correct Answer is ["60"]
Explanation
Here's how to calculate the gentamicin dosage per dose for the child:
Client weight conversion:
Client weight: 66 lbs
We need the weight in kilograms (kg) for the medication dosage.
Conversion factor: 1 kg = 2.205 lbs
Client weight (kg) = 66 lbs / 2.205 lbs/kg = 30 kg (round to nearest whole number)
Gentamicin dosage:
Prescribed dose: 2 mg/kg/dose (given)
Calculate the total gentamicin amount per dose:
Total dose (mg/dose) = Dose (mg/kg/dose) x Client weight (kg)
Total dose (mg/dose) = 2 mg/kg/dose * 30 kg
Total dose (mg/dose) = 60 mg (round to nearest whole number)
Therefore, the child should receive 60 mg of gentamicin sulfate per dose.
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