Stasis of urine in the bladder may promote bacterial growth, leading to local and ascending infection to the:

Choice A reason: While obesity can be associated with hypercholesterolemia, this condition primarily affects lipid levels and cardiovascular health rather than directly impairing insulin circulation.

Choice B reason: Obesity is not solely a result of high sugar intake. While diet plays a role, obesity involves a complex interplay of genetic, environmental, and lifestyle factors. High sugar intake can contribute to weight gain, but it is not the direct cause of obesity.

Choice C reason: Obesity releases fatty acids and cytokines, which interfere with insulin receptors. Adipose tissue in obese individuals releases pro-inflammatory cytokines and fatty acids that can cause insulin resistance by interfering with insulin signaling pathways.

Choice D reason: Obesity is not directly associated with a mutation of the MiR-21 gene. While genetic factors can contribute to obesity and type 2 diabetes, the primary mechanism involves metabolic and inflammatory pathways rather than specific gene mutations.

Choice A reason: The overall goal of treatment for both type 1 and type 2 diabetes is to maintain blood glucose levels within a normal range and prevent complications. While the strategies to achieve these goals may differ, the ultimate objectives are similar for both types of diabetes.

Choice B reason: The treatment for type 1 diabetes primarily involves insulin therapy, as the body cannot produce insulin. In contrast, type 2 diabetes treatment often starts with lifestyle changes and oral medications to improve insulin sensitivity and control blood glucose levels. Insulin therapy may be required later in the course of type 2 diabetes if other treatments are insufficient.

Choice C reason: Both types of diabetes are diagnosed using similar criteria, including measuring blood glucose levels through fasting blood glucose tests, oral glucose tolerance tests, and HbA1c levels. The diagnosis process itself is not a major differentiating factor between the two types.

Choice D reason: The potential long-term complications of both type 1 and type 2 diabetes are similar and include cardiovascular disease, neuropathy, nephropathy, retinopathy, and other complications related to prolonged high blood glucose levels. While the risk factors and progression may vary, the types of complications are not significantly different between the two conditions.