Nitroglycerin 125 mg diluted in 500 mL of D5W (dextrose 5% in water) is infusing at a rate of 42 mcg/minute for a patient with chest pain.
What rate (in mL/hr) should the nurse program into the IV pump to deliver this dose? Round your answer to the nearest tenth.

To find the milliliters per hour, you need to calculate the following:

- The patient's weight in kilograms
- The dose of Principen in milligrams
- The infusion rate in milliliters per hour using the formula: Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

First, convert the patient's weight from pounds to kilograms by dividing by 2.2:

22 lb / 2.2 = 10 kg

Next, multiply the patient's weight by the dose of Principen per kilogram to get the total dose in milligrams:

10 kg x 25 mg/kg = 250 mg

Then, use the formula for infusion rate to find how many milliliters per hour the IV pump should deliver:

Infusion rate (mL/h) = (Total volume (mL) x Flow factor (gt/mL)) / Time (min) x 60 min/h

Since the medication is prepared in 50 mL of solution and the infusion time is 30 minutes, plug in these values into the formula:

Infusion rate (mL/h) = (50 mL x 1 gt/mL) / 30 min x 60 min/h

Simplify and solve for the infusion rate:

Infusion rate (mL/h) = 100 mL/h

Therefore, the nurse should administer **100 mL/h** to infuse Principen 250 mg over 30 minutes.

Insulin is a hormone that helps regulate blood sugar levels. It is usually injected into the fat layer just under the skin (subcutaneous or SubQ) using a syringe and needle or a pen-like device². Insulin syringes are marked in units of insulin, not milliliters or cubic centimeters. The most common insulin syringe holds 1 mL of fluid and has markings for 100 units of insulin². A U-100 syringe means that for every 1 mL of fluid, there are 100 units of insulin³.
To administer 14 units of insulin, you would need to draw up 0.14 mL of fluid in a U-100 syringe. You would inject the insulin into your abdomen, upper arm, butocks, hip, or the front or side of the thigh¹. You would use a different area within the site each time you inject insulin to prevent lumps, swelling, or thickened skin¹.

The other options are incorrect because:

b) There is no need to divide the dose into two injections. This would increase the risk of infection and pain.

c) A tuberculin syringe is not designed for insulin administration. It is marked in milliliters or cubic centimeters, not units of insulin. Using a tuberculin syringe could result in an incorrect dose of insulin.

d) The timing of insulin administration depends on the type and duration of insulin. Some insulins are taken before meals, some are taken after meals, and some are taken once or twice a day. The primary healthcare provider should specify when to take the insulin.