Jo is a client with Type 1 Diabetes. Jo has a blood glucose level of 644 mg/dL. The nurse interprets that this client is most at risk of developing which type of acid-base imbalance?

Choice A reason: Burning pain and tingling in extremities are not symptoms of autonomic neuropathy, but of peripheral neuropathy. Peripheral neuropathy affects the sensory and motor nerves that innervate the skin, muscles, and joints. It can cause pain, numbness, weakness, and loss of sensation in the extremities. Autonomic neuropathy affects the nerves that control the involuntary functions of the body, such as digestion, blood pressure, heart rate, and sweating.

Choice B reason: Nausea and feeling of abdominal fullness are symptoms of autonomic neuropathy, specifically of gastroparesis. Gastroparesis is a condition where the stomach muscles are weakened or paralyzed, and cannot move food properly. It can cause delayed gastric emptying, nausea, vomiting, bloating, early satiety, and poor blood glucose control. Autonomic neuropathy can damage the vagus nerve, which regulates the stomach motility and secretion.

Choice C reason: Elevated blood pressure and delayed capillary refill are not symptoms of autonomic neuropathy, but of cardiovascular problems. Blood pressure is the force of blood against the walls of the arteries, and capillary refill is the time it takes for the color to return to the nail bed after pressing on it. Elevated blood pressure can indicate hypertension, which is a risk factor for heart disease and stroke. Delayed capillary refill can indicate poor blood circulation, which can be caused by atherosclerosis, peripheral artery disease, or shock. Autonomic neuropathy can affect the blood pressure and heart rate, but usually causes hypotension and tachycardia, not hypertension and delayed capillary refill.

Choice D reason: Increased thirst and excessive urination are not symptoms of autonomic neuropathy, but of diabetes mellitus. Diabetes mellitus is a condition where the body cannot produce or use insulin properly, and the blood glucose level becomes too high. Increased thirst and excessive urination are signs of hyperglycemia, which is a high blood glucose level. Hyperglycemia can cause dehydration, electrolyte imbalance, and ketoacidosis. Autonomic neuropathy can be a complication of diabetes mellitus, but it does not cause increased thirst and excessive urination.

Choice A reason: Urine dipstick for glucose is not a reliable test to evaluate the effectiveness of treatment for type 2 diabetes. Urine glucose testing can only detect glucose in the urine when the blood glucose level is very high, above the renal threshold of 180 mg/dL. Urine glucose testing does not reflect the average blood glucose level over time, and can be affected by factors such as hydration, medication, and urinary tract infections.

Choice B reason: Fasting blood glucose is a test that measures the blood glucose level after an overnight fast of at least 8 hours. Fasting blood glucose is a useful test to diagnose diabetes, but it is not the best test to evaluate the effectiveness of treatment for type 2 diabetes. Fasting blood glucose only reflects the blood glucose level at one point in time, and can vary depending on the time of day, the amount and type of food eaten, and the activity level.

Choice C reason: Oral glucose tolerance is a test that measures the blood glucose level before and after drinking a solution containing 75 g of glucose. Oral glucose tolerance is another test that can diagnose diabetes, but it is not the most convenient or accurate test to evaluate the effectiveness of treatment for type 2 diabetes. Oral glucose tolerance requires the patient to fast for at least 8 hours, drink the glucose solution, and have blood samples taken at 0, 30, 60, 90, and 120 minutes. Oral glucose tolerance can also be influenced by factors such as stress, illness, medication, and menstrual cycle.

Choice D reason: Glycosylated hemoglobin (Hemoglobin A1C) is a test that measures the percentage of hemoglobin that has glucose attached to it. Hemoglobin is a protein in the red blood cells that carries oxygen. Red blood cells have a lifespan of about 120 days, so the hemoglobin A1C test reflects the average blood glucose level over the past 2 to 3 months. Hemoglobin A1C is the best test to evaluate the effectiveness of treatment for type 2 diabetes, as it shows how well the blood glucose level has been controlled over time, and is not affected by factors such as fasting, food intake, or daily fluctuations.