The nurse is caring for a patient who has diabetes and complains of chronic, burning leg pain even when taking oxycodone (OxyContin) twice daily. Which prescribed medication is the best choice for the nurse to administer as an adjuvant to decrease the patient's pain?

Choice A reason: Administration of an anti-diarrheal is not the appropriate management for an 18-month-old with severe dehydration and weight loss secondary to acute diarrhea and vomiting. Anti-diarrheals are not recommended for children under 5 years, as they can have serious side effects, such as paralytic ileus, toxic megacolon, and worsening of dehydration. Anti-diarrheals do not address the underlying cause of diarrhea, and may prolong the duration of infection or toxin exposure.

Choice B reason: Clear liquids, 1 to 2 ounces at a time, are not sufficient to treat an 18-month-old with severe dehydration and weight loss secondary to acute diarrhea and vomiting. Clear liquids, such as water, tea, or broth, do not contain enough electrolytes, such as sodium, potassium, and bicarbonate, to replace the losses from diarrhea and vomiting. Clear liquids may also dilute the blood sodium level and cause hyponatremia, a condition of low sodium in the blood, which can lead to seizures, coma, and death.

Choice C reason: Oral rehydration solution (ORS) is the best management for an 18-month-old with severe dehydration and weight loss secondary to acute diarrhea and vomiting. ORS is a specially formulated solution that contains water, glucose, and electrolytes in the right proportions to replenish the fluid and electrolyte losses from diarrhea and vomiting. ORS can prevent or treat dehydration, and reduce the need for intravenous fluids. ORS can be given by mouth, spoon, cup, or syringe, depending on the child's ability to drink. The amount of ORS to give depends on the degree of dehydration and the weight of the child. The nurse should follow the guidelines from the World Health Organization (WHO) or the local health authority for the appropriate dosage and frequency of ORS administration¹.

Choice D reason: Intravenous fluids are not the first-line management for an 18-month-old with severe dehydration and weight loss secondary to acute diarrhea and vomiting. Intravenous fluids are only indicated for children who have severe dehydration and are unable to drink or tolerate ORS, or who have signs of shock, such as weak pulse, cold extremities, or altered consciousness. Intravenous fluids require hospitalization, skilled personnel, and sterile equipment, and carry the risk of infection, overhydration, or electrolyte imbalance. Intravenous fluids should be given according to the WHO or the local health authority guidelines, and should be switched to ORS as soon as the child is able to drink¹.

Choice A reason: This statement is false. A sugar-water pacifier does not help the vaccination be more effective. Vaccinations are effective because they stimulate the immune system to produce antibodies against a specific disease.

Choice B reason: This statement is false. A sugar-water pacifier does not prevent hypoglycemia from the stress of the injection. Hypoglycemia is a condition where the blood sugar level is too low, which can cause symptoms such as sweating, trembling, confusion, or seizures. A sugar-water pacifier does not provide enough glucose to prevent hypoglycemia.

Choice C reason: This statement is false. A sugar-water pacifier does not provide additional calories to prevent malnourishment. Malnourishment is a condition where the body does not get enough nutrients, such as protein, vitamins, and minerals, to function properly. A sugar-water pacifier does not provide enough nutrients to prevent malnourishment.

Choice D reason: This statement is true. A sugar-water pacifier soothes and distracts the infant from pain. Sugar-water has a sweet taste that activates the endorphin system, which reduces pain perception. A pacifier also provides oral stimulation and comfort, which distracts the infant from the pain of the injection.