In which stage of the HIV lifecycle does the enzyme integrase play a crucial role, and what is its function in that stage?

Assembly. Integrase packages the viral RNA into new virions.

Integration: Integrase inserts viral DNA into the host's genome.

Entry: Integrase helps the virus fuse with the host cell membrane.

Reverse Transcription: Integrase copies viral RNA into DNA.

Answer and Explanation

The Correct Answer is B

A. In the assembly stage, other proteins and enzymes are involved in the packaging of viral components into new virions, not integrase.
B. During the integration stage, integrase is essential as it inserts the newly formed viral DNA into the host's genome, enabling the virus to utilize the host's cellular machinery for replication.
C. Integrase does not participate in the entry stage; this stage is facilitated by other proteins that aid in the fusion of the virus with the host cell membrane.
D. Integrase is not involved in reverse transcription; that process is facilitated by the enzyme reverse transcriptase, which converts viral RNA into DNA.

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Correct Answer is ["A","C"]

Explanation

A. Orthostatic hypotension is a common sign of hypovolemia, as the lack of fluid volume can lead to a drop in blood pressure when changing positions.
B. Bradycardia is not typically associated with fluid volume deficit; tachycardia is more common as the body tries to compensate for low blood volume.
C. Decreased skin turgor is a classic sign of dehydration and fluid volume deficit, indicating reduced skin elasticity.
D. Weight gain is associated with fluid volume overload, not deficit.
E. Pulmonary edema is related to fluid volume overload or congestive heart failure, not hypovolemia.

A. IV antibiotics B. Urinalysis C. Chest x-ray D. Chest tube placement E. Admit to inpatient F. Airborne precautions G. Draw an STI lab panel H. Complete blood count

Correct Answer is ["A","C","E","H"]

Explanation

The nurse anticipates the following orders from the provider based on the suspected diagnosis:

A. IV antibiotics: To treat the suspected infection.
C. Chest x-ray: To assess the lungs for signs of infection, such as pneumonia.
E. Admit to inpatient: The client's worsening condition and need for aggressive treatment warrant hospitalization.
H. Complete blood count: To assess the client's overall health status and identify any abnormalities, such as anemia or infection.

Rationale:

B. Urinalysis: While a urinalysis can be helpful in assessing for urinary tract infections, it is not a priority in this case.
D. Chest tube placement: This is not indicated unless the client develops a pleural effusion or pneumothorax.
F. Airborne precautions: This is not necessary for the client's current condition.
G. Draw an STI lab panel: While this may be relevant for the client's overall health, it is not a priority at this time, especially given the client's acute presentation.

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In which stage of the HIV lifecycle does the enzyme integrase play a crucial role, and what is its function in that stage?

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Naxlex Comprehensive Predictor Exams

Which of the following signs are commonly associated with fluid volume deficit (hypovolemia)? (Select All that Apply.)

Correct Answer is ["A","C"]

Explanation

A nurse is caring for a client in the clinic. Exhibits The nurse anticipates which of the following orders from the provider based on the suspected diagnosis? (Select all that apply)

Correct Answer is ["A","C","E","H"]

Explanation

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