In which stage of the HIV lifecycle does the enzyme integrase play a crucial role, and what is its function in that stage?

Assembly. Integrase packages the viral RNA into new virions.

Integration: Integrase inserts viral DNA into the host's genome.

Entry: Integrase helps the virus fuse with the host cell membrane.

Reverse Transcription: Integrase copies viral RNA into DNA.

Answer and Explanation

The Correct Answer is B

A. In the assembly stage, other proteins and enzymes are involved in the packaging of viral components into new virions, not integrase.
B. During the integration stage, integrase is essential as it inserts the newly formed viral DNA into the host's genome, enabling the virus to utilize the host's cellular machinery for replication.
C. Integrase does not participate in the entry stage; this stage is facilitated by other proteins that aid in the fusion of the virus with the host cell membrane.
D. Integrase is not involved in reverse transcription; that process is facilitated by the enzyme reverse transcriptase, which converts viral RNA into DNA.

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Correct Answer is D

Explanation

A. Increasing the infusion rate may exacerbate the patient's symptoms and does not address the potential toxicity from the furosemide.
B. Normal potassium levels indicate that potassium supplementation is unnecessary and does not address the dizziness and ringing in the ears, which could suggest ototoxicity from furosemide.
C. While reassurance can help, the patient's symptoms indicate a potential adverse reaction to the medication that should not be ignored.
D. Stopping the furosemide infusion and notifying the provider is the most appropriate action due to the risk of ototoxicity and the need for further evaluation of the patient's symptoms.

A. Orthostatic hypotension B. Bradycardia C. Decreased skin turgor D. Weight gain E. Pulmonary edema

Correct Answer is ["A","C"]

Explanation

A. Orthostatic hypotension is a common sign of hypovolemia, as the lack of fluid volume can lead to a drop in blood pressure when changing positions.
B. Bradycardia is not typically associated with fluid volume deficit; tachycardia is more common as the body tries to compensate for low blood volume.
C. Decreased skin turgor is a classic sign of dehydration and fluid volume deficit, indicating reduced skin elasticity.
D. Weight gain is associated with fluid volume overload, not deficit.
E. Pulmonary edema is related to fluid volume overload or congestive heart failure, not hypovolemia.

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In which stage of the HIV lifecycle does the enzyme integrase play a crucial role, and what is its function in that stage?

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Naxlex Comprehensive Predictor Exams

A 70-year-old male receiving high-dose IV furosemide for heart failure complains of ringing in his ears and dizziness. His current labs show normal potassium and sodium levels. What is the nurse's most appropriate intervention?

Correct Answer is D

Explanation

Which of the following signs are commonly associated with fluid volume deficit (hypovolemia)? (Select All that Apply.)

Correct Answer is ["A","C"]

Explanation

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In which stage of the HIV lifecycle does the enzyme integrase play a crucial role, and what is its function in that stage?

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