Anticholinergic drugs are used in Ophthalmology because they produce what effect?

Choice A rationale

Parkinson's disease is characterized by an imbalance of dopamine and acetylcholine, primarily due to the degeneration of dopamine-producing neurons in the substantia nigra. This imbalance results in the characteristic motor symptoms of Parkinson's disease, such as tremors, rigidity, and bradykinesia.

Choice B rationale

Parkinson's disease involves decreased dopamine production, not increased. The disease is caused by the progressive loss of dopamine-producing neurons in the brain, leading to reduced dopamine levels and an imbalance with acetylcholine.

Choice C rationale

Alzheimer's disease is not primarily characterized by a decrease in dopamine. Instead, it involves the degeneration of cholinergic neurons and a deficiency in acetylcholine, which is crucial for memory and cognitive functions.

Choice D rationale

Alzheimer's disease is associated with a deficiency of acetylcholine rather than an excess. The disease is also characterized by the presence of neuritic plaques and neurofibrillary tangles in the brain, which contribute to cognitive decline.

Choice A rationale

Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.

Choice B rationale

Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.

Choice C rationale

Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.

Choice D rationale

Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.