An older female client comes to the clinic for a regular check-up. The client tells the nurse that she has increased her daily doses of acetaminophen for the past month to control joint pain. Based on this patient's comment, which previous laboratory results should the nurse compare with today's laboratory report?

A) 40-year-old female with frequent vaginal infections: Simvastatin is a medication used primarily to manage cholesterol levels and reduce the risk of cardiovascular diseases. Frequent vaginal infections are not directly related to cholesterol levels or cardiovascular risk. Therefore, this client is unlikely to benefit from education about simvastatin.
B) A 50-year-old male with a history of angina: Simvastatin is a statin medication prescribed to lower cholesterol levels and reduce the risk of cardiovascular events, such as heart attacks and strokes. Since angina is a symptom of coronary artery disease, a condition often related to high cholesterol levels, this client would benefit from education about simvastatin, which can help manage cholesterol and potentially reduce cardiovascular risk.
C) An 18-year-old pregnant female with type 1 diabetes mellitus: Statins, including simvastatin, are generally contraindicated during pregnancy due to potential risks to the developing fetus. Additionally, this client’s primary condition of type 1 diabetes mellitus would not typically be managed with simvastatin alone. Therefore, this client is not the target for simvastatin education.
D) A 75-year-old male with bone cancer: While simvastatin is used for managing cholesterol and preventing cardiovascular events, bone cancer is not directly related to cholesterol levels. The primary focus for this client would be managing cancer-related symptoms and treatments rather than cholesterol levels. Thus, this client would not benefit from education about simvastatin.

A) Coronary artery disease: It is crucial to assess for a history of coronary artery disease (CAD) before administering sumatriptan, as the medication is a serotonin receptor agonist that can cause vasoconstriction of coronary arteries. This can increase the risk of serious cardiovascular events, such as heart attack or stroke, particularly in clients with preexisting CAD.

B) Seasonal allergic rhinitis: While seasonal allergic rhinitis may be a concern for other medications due to potential allergic reactions or interactions, it is not directly related to the administration of sumatriptan. This condition does not pose a significant risk with the use of sumatriptan.

C) Type 2 diabetes mellitus: Although type 2 diabetes mellitus is an important consideration in the overall health management of a client, it is not the most critical condition to assess before administering sumatriptan. However, if the client has diabetes with associated complications like cardiovascular disease, this would increase concern for using sumatriptan.

D) Irritable bowel syndrome: Irritable bowel syndrome (IBS) is a gastrointestinal disorder that typically does not influence the decision to administer sumatriptan. While IBS may affect a client’s comfort or medication regimen, it does not present the same immediate risks as coronary artery disease when using sumatriptan.