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An adult client receives a prescription for diphenhydramine 15 mL PO every 12 hours PRN for pruritus. The bottle is labeled, "Diphenhydramine 12.5 mg/5 mL." What is the total daily dose in mg that the client receives? (Enter numerical value only.)
Answer and Explanation

The Correct Answer is ["75"]

Dose per administration in milliliters = 15 mL.

Concentration of the medication = 12.5 mg/5 mL.

  • Calculate the amount of medication in milligrams (mg) per administration.

Amount per administration (mg) = Dose per administration (mL) × (Concentration (mg) / Volume (mL))

     = 15 mL × (12.5 mg / 5 mL)

                     = 15 mL × 2.5 mg/mL

     = 37.5 mg.

  • Determine the number of doses per day.

Doses are given every 12 hours, so Number of doses per day = 24 hours / 12 hours/dose 

 = 2 doses/day.

  • Calculate the total daily dose in milligrams (mg).

Total daily dose (mg) = Amount per administration (mg) × Number of doses per day

           = 37.5 mg × 2 doses

           = 75 mg.


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Related Questions

Correct Answer is C

Explanation

A. Iron-rich meats: While iron is essential for preventing anemia, it does not contribute significantly to bone mineral density. These foods are not a primary recommendation for osteoporosis prevention, which focuses on calcium and vitamin D intake.

B. Water and herbal teas: Adequate hydration is important for overall health, but water and herbal teas do not contain the calcium or vitamin D needed to support bone health. They have minimal direct impact on preventing osteoporosis.

C. Low fat dairy products: Low fat dairy products like milk, yogurt, and cheese are rich in calcium and often fortified with vitamin D—both critical nutrients for maintaining bone density and preventing osteoporosis.

D. Fresh fruits and vegetables: Fruits and vegetables provide general nutritional support, but are not the most concentrated sources of bone-building nutrients like calcium. They support health broadly but are not the key dietary focus for osteoporosis.

Correct Answer is ["0.6"]

Explanation

Rationale:

  • Convert the client's weight from pounds (lb) to kilograms (kg).

Weight in kg = 154 lb / 2.2 lb/kg

= 70 kg.

  • Calculate the total desired dose in units.

Desired dose (units) = Desired dose (units/kg) × Weight (kg)

= 200 units/kg × 70 kg

= 14000 units.

Available concentration of the medication = 25,000 units/mL.

  • Calculate the volume in milliliters (mL) to administer.

Volume (mL) = Desired dose (units) / Available concentration (units/mL)

= 14000 units / 25000 units/mL

= 0.56 mL.

  • Round the answer to the nearest tenth.

= 0.6.

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