ACE inhibitors work on the RAAS to prevent the conversion of angiotensin I to angiotensin II. Because this blocking occurs in the cells in the lung, which is usually the site of this conversion, the use of ACE inhibitors often results in
unrelenting cough.
respiratory depression.
spontaneous pneumothorax.
pneumonia.
The Correct Answer is A
This is the correct response. ACE inhibitors are known to cause a persistent, dry, and irritating cough in some individuals. This adverse effect occurs due to the accumulation of bradykinin and other substances in the lungs, leading to increased sensitivity of the cough reflex. The cough typically resolves upon discontinuation of the ACE inhibitor.
B) Respiratory depression:
Respiratory depression is not a common side effect of ACE inhibitors. ACE inhibitors do not directly affect respiratory drive or function in the central nervous system. Therefore, this option is incorrect.
C) Spontaneous pneumothorax:
Spontaneous pneumothorax is not a typical adverse effect associated with ACE inhibitor use. ACE inhibitors do not directly cause the development of pneumothorax, which is characterized by the presence of air in the pleural space. Therefore, this option is incorrect.
D) Pneumonia:
While ACE inhibitors can increase the risk of respiratory infections due to their effect on the immune system, pneumonia is not a specific adverse effect associated with ACE inhibitor use. Pneumonia is typically caused by infectious agents such as bacteria, viruses, or fungi, rather than being a direct effect of ACE inhibitors. Therefore, this option is incorrect.”
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A) Glaucoma:
While propranolol can exacerbate symptoms of glaucoma, it is not an absolute contraindication. However, caution is warranted in clients with glaucoma due to its potential to increase intraocular pressure.
B) Depression:
Propranolol is not contraindicated in clients with a history of depression. In fact, it is sometimes used to manage anxiety symptoms associated with certain types of depression.
C) Asthma:
Propranolol is contraindicated in clients with a history of asthma or bronchospasm because it can exacerbate bronchoconstriction and potentially precipitate an acute asthma attack.
D) Migraines:
Propranolol is often used prophylactically in clients with migraines to reduce the frequency and severity of attacks. It is not contraindicated in clients with a history of migraines."
Correct Answer is ["100"]
Explanation
We are given the following information:
Medication: Ticarcillin/clavulanate 3.1 g
Administration route: Intermittent IV bolus over 30 minutes
Available solution: Ticarcillin/clavulanate 3.1 g in 50 mL 0.9% sodium chloride (NSS)
However, the IV pump controls the rate of delivery over time (usually in hours). An intermittent bolus means the medication is infused all at once over a shorter period (30 minutes in this case).
The pump rate calculation here focuses on the total volume of the available solution containing the medication to be delivered, not necessarily on the medication amount itself.
Therefore, we need to find the rate at which the total volume of 50 mL solution should be delivered over 30 minutes.
Conversion is necessary because pump rates are typically set in hours (hr).
Time (hours) = 30 minutes / 60 minutes/hour = 0.5 hours
Now, calculate the flow rate:
Flow rate (mL/hr) = Total volume (mL) / Infusion time (hours)
Flow rate (mL/hr) = 50 mL / 0.5 hours = 100 mL/hr
Round to the nearest whole number as requested.
Therefore, the nurse should set the pump to deliver approximately 100 mL/hr. This ensures the total 50 mL solution containing the 3.1 g of ticarcillin/clavulanate is delivered over the intended 30-minute period.
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