Absolute contraindications to vaccine administration in children include (select all that apply)
A History of anaphylactic reaction to a specific vaccine or vaccine component
Moderate local reaction following a dose of an injectable vaccine
Presence of moderate or severe illnesses with or without a fever
Current treatment with antimicrobial medication
Correct Answer : A,C
Choice A rationale: A history of anaphylactic reaction to a specific vaccine or its components is a contraindication, as it indicates a severe allergic response.
Choice B rationale: A moderate local reaction to a vaccine is not an absolute contraindication. It may be considered when weighing risks and benefits.
Choice C rationale: The presence of moderate or severe illnesses, with or without a fever, is an absolute contraindication, as vaccines may exacerbate existing illness.
Choice D rationale: Current treatment with antimicrobial medication is not an absolute contraindication to vaccination in children.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale: Testing for CYP450 genetic variants is more relevant for medications metabolized by the cytochrome P450 system.
Choice B rationale: HLA-B genetic variants are more associated with certain drug hypersensitivity reactions, not specifically for etanercept.
Choice C rationale: Etanercept can increase the risk of reactivating latent infections, including hepatitis B. Screening for latent hepatitis B virus is essential before starting therapy.
Choice D rationale: Blood type and crossmatch are not typically required for starting etanercept therapy.
Correct Answer is B
Explanation
Choice A rationale: Stopping aspirin immediately may not be necessary and can increase the risk of rebound thrombosis. A gradual discontinuation is often recommended.
Choice B rationale: Stopping aspirin 3 days prior to surgery is a common recommendation to minimize the risk of bleeding during and after the surgical procedure.
Choice C rationale: Reducing the aspirin dosage may not be sufficient, and complete discontinuation is often advised before surgery.
Choice D rationale: Continuing aspirin as scheduled can increase the risk of bleeding during and after surgery. It is generally recommended to discontinue aspirin before elective surgical procedures.
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