A patient diagnosed with rheumatoid arthritis is about to begin therapy with Etanercept, a tumor necrosis factor antagonist. The nurse anticipates the patient will be tested for
CYP450 genetic variants.
HLA-B genetic variants.
latent hepatitis B virus.
Blood type and crossmatch.
The Correct Answer is C
Choice A rationale: Testing for CYP450 genetic variants is more relevant for medications metabolized by the cytochrome P450 system.
Choice B rationale: HLA-B genetic variants are more associated with certain drug hypersensitivity reactions, not specifically for etanercept.
Choice C rationale: Etanercept can increase the risk of reactivating latent infections, including hepatitis B. Screening for latent hepatitis B virus is essential before starting therapy.
Choice D rationale: Blood type and crossmatch are not typically required for starting etanercept therapy.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale: Norepinephrine is a neurotransmitter that is active in both the peripheral and central nervous systems.
Choice B rationale: Serotonin is primarily active in the central nervous system.
Choice C rationale: Substance P is a neurotransmitter that functions more in the peripheral nervous system.
Choice D rationale: Dynorphins primarily function in the central nervous system.
Correct Answer is B
Explanation
Choice A rationale: Stopping aspirin immediately may not be necessary and can increase the risk of rebound thrombosis. A gradual discontinuation is often recommended.
Choice B rationale: Stopping aspirin 3 days prior to surgery is a common recommendation to minimize the risk of bleeding during and after the surgical procedure.
Choice C rationale: Reducing the aspirin dosage may not be sufficient, and complete discontinuation is often advised before surgery.
Choice D rationale: Continuing aspirin as scheduled can increase the risk of bleeding during and after surgery. It is generally recommended to discontinue aspirin before elective surgical procedures.
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