A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.
Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?
22 mg
486 mg
44 mg
47 mg
The Correct Answer is C
We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.
BSA = 0.007184 × W^0.425 × H^0.725.
where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725
BSA = 2.15 m².
Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.
Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.
The total dose for 5 days is:.
Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days
Total dose = 215 mg.
Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.
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Related Questions
Correct Answer is B
Explanation
To calculate the dose of dobutamine in mg/hr, we need to convert the patient's weight from pounds (lb) to kilograms (kg) and then use the ordered dose of 10 mcg/kg/min.
1 lb = 0.453592 kg (rounded to 6 decimal places) Patient's weight in kg = 110 lb x 0.453592 kg/lb
Patient's weight in kg = 49.89512 kg (rounded to 5 decimal places)
Now we can calculate the dose of dobutamine in mg/hr using the following formula:
Dose (in mg/hr) = Weight (in kg) x Dose (in mcg/kg/min) x 60 (to convert minutes to hours) / 1000 (to convert mcg to mg)
Dose (in mg/hr) = 49.89512 kg x 10 mcg/kg/min x 60 / 1000
Dose (in mg/hr) = 29.937072 mg/hr (rounded to 3 decimal places)
Therefore, the patient should receive a dose of approximately 29.9 mg/hr of dobutamine.
Correct Answer is A
Explanation
To calculate the total amount of heparin, we need to multiply the infusion rate by the time and then by the concentration of heparin in the IV bag. From 9:00 a.m. to 11:00 a.m., the infusion rate was 12 mL/hr, so the amount of heparin infused in this period was 12 mL/hr x 2 hours x 100 units/mL = 2400 units.
From 11:00 a.m. to 2:00 p.m., the infusion rate was 10 mL/hr, so the amount of heparin infused in this period was 10 mL/hr x 3 hours x 100 units/mL = 3000 units. The total amount of heparin infused from 9:00 a.m. to 2:00 p.m. was 2400 units + 3000 units = 5400 units.
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