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A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.

Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?

A.

22 mg

B.

486 mg

C.

44 mg

D.

47 mg

Answer and Explanation

The Correct Answer is C

We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.

BSA = 0.007184 × W^0.425 × H^0.725.

where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725

BSA = 2.15 m².

Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.

Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.

The total dose for 5 days is:.

Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days

Total dose = 215 mg.

Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.


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Related Questions

Correct Answer is A

Explanation

To calculate the total amount of heparin, we need to multiply the infusion rate by the time and then by the concentration of heparin in the IV bag. From 9:00 a.m. to 11:00 a.m., the infusion rate was 12 mL/hr, so the amount of heparin infused in this period was 12 mL/hr x 2 hours x 100 units/mL = 2400 units.

From 11:00 a.m. to 2:00 p.m., the infusion rate was 10 mL/hr, so the amount of heparin infused in this period was 10 mL/hr x 3 hours x 100 units/mL = 3000 units. The total amount of heparin infused from 9:00 a.m. to 2:00 p.m. was 2400 units + 3000 units = 5400 units.

Correct Answer is C

Explanation

To calculate the drug dosage, multiply the prescribed dose per kilogram by the client’s weight in kilograms:

0.5 mg/kg x 57 kg = 28.5 mg

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