A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.
Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?
22 mg
486 mg
44 mg
47 mg
The Correct Answer is C
We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.
BSA = 0.007184 × W^0.425 × H^0.725.
where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725
BSA = 2.15 m².
Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.
Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.
The total dose for 5 days is:.
Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days
Total dose = 215 mg.
Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.

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Related Questions
Correct Answer is B
Explanation
We can use the following formula to calculate the infusion time:
Infusion time (in hours) = Remaining volume (in mL) / Infusion rate (in mL/hr)
First, let's convert the current time to minutes since we will be calculating the infusion time in minutes as well:
19:30 = 19 hours x 60 minutes/hour + 30 minutes = 1170 minutes Now we can substitute the given values into the formula:
Infusion time (in hours) = 376 mL / 40 mL/hr Infusion time (in hours) = 9.4 hours
To convert this to hours and minutes, we can separate the integer and decimal parts of the answer:
9 hours (integer part) and 0.4 hours x 60 minutes/hour = 24 minutes (decimal part)
Therefore, the infusion time is 9 hours and 24 minutes, and the infusion will finish at approximately 04:54 (19:30 + 9 hours and 24 minutes).
Correct Answer is C
Explanation
To calculate the rate per hour, divide the amount of magnesium sulfate to be administered by the concentration of magnesium sulfate in the IV bag:
6 grams ÷ 40 grams = 0.15
Then, multiply the result by the volume of the IV bag, which is usually 1000 mL: 0.15 x 1000 mL = 150 mL
This is the amount of fluid that contains 6 grams of magnesium sulfate. To administer this amount over 30 minutes, multiply by 2 to get the rate per hour:
150 mL x 2 = 300 mL/hr.
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