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A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.

Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?

A.

22 mg

B.

486 mg

C.

44 mg

D.

47 mg

Answer and Explanation

The Correct Answer is C

We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.

BSA = 0.007184 × W^0.425 × H^0.725.

where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725

BSA = 2.15 m².

Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.

Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.

The total dose for 5 days is:.

Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days

Total dose = 215 mg.

Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.


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Related Questions

Correct Answer is D

Explanation

To calculate the amount of magnesium sulfate to be added to the normal saline, we can use the formula:

Concentration = Dose / Volume Plugging in the given values, we get:

Concentration = 2 g / 50 mL Simplifying, we get:

Concentration = 0.04 g/mL

To find the amount of magnesium sulfate needed for 1000 mL of normal saline, we can multiply the concentration by the volume:

Amount = Concentration × Volume Amount = 0.04 g/mL × 1000 mL Amount = 40 g

Therefore, 40 g of magnesium sulfate must be added to 1000 mL of normal saline to provide the ordered infusion.

Correct Answer is C

Explanation

We can use the following formula to calculate the infusion rate:

Infusion rate (mL/hr) = (Dose ordered in mcg/min x Volume to be infused in mL) / Dose available in mg

First, we need to convert the dose ordered from mg/min to mcg/min: 125 mg = 125,000 mcg

125,000 mcg/500 mL = 250 mcg/mL

Now we can plug in the values we have into the formula:

Infusion rate (mL/hr) = (42 mcg/min x 60 min x 24 hours) / (250 mcg/mL) Infusion rate (mL/hr) = 10.08 mL/hr

Rounding to the nearest tenth, the answer is C. 10.1 mL/hr.

Therefore, the nurse should program the IV pump to deliver the nitroglycerin at a rate of 10.1 mL/hr to achieve the ordered dose of 42 mcg/minute.

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