A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.
Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?
22 mg
486 mg
44 mg
47 mg
The Correct Answer is C
We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.
BSA = 0.007184 × W^0.425 × H^0.725.
where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725
BSA = 2.15 m².
Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.
Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.
The total dose for 5 days is:.
Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days
Total dose = 215 mg.
Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.

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Related Questions
Correct Answer is C
Explanation
To calculate the dose that the child receives, we need to first convert the volume of the suspension from teaspoons to milliliters. One teaspoon is equal to 5 milliliters, so 2 teaspoons is equal to 10 milliliters. Then, we can use the concentration of the suspension to find the amount of cefuroxime in 10 milliliters. The concentration is 25 mg in 2 mL, or 12.5 mg in 1 mL. Therefore, the amount of cefuroxime in 10 mL is:
10 mL × 12.5 mg/mL = 125 mg
Therefore, the child receives 125 mg of cefuroxime once a day orally.
Correct Answer is B
Explanation
To calculate the infusion rate in mL/hr, we need to divide the total volume to be infused by the time for infusion and convert the units appropriately.
First, we need to convert the time of infusion from hours to minutes, since most IV pumps use minutes as the time unit.
2 hours x 60 minutes/hour = 120 minutes Next, we can calculate the infusion rate:
500 mL ÷ 120 minutes = 4.17 mL/minute
To convert mL/minute to mL/hour, we multiply by 60:
4.17 mL/minute x 60 minutes/hour = 250 mL/hour
Therefore, the correct answer is B. 250 mL/hr. The nurse should set the IV pump to deliver the LR infusion at a rate of 250 mL/hr to infuse 500 mL over 2 hours.
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