A physician orders Platinol (cisplatin) 20 mg/m²/day x 5 days IV for a patient weighing 94.5 kg and having a height of 185 cm.
Using the body surface area (BSA) formula, what would this patient's dose be in milligrams?
22 mg
486 mg
44 mg
47 mg
The Correct Answer is C
We need to calculate the patient's BSA using one of the available formulas. The most widely used formula is the Du Bois formula, which is:.
BSA = 0.007184 × W^0.425 × H^0.725.
where W is weight in kg and H is height in cm.. Plugging in the patient's weight and height, we get:. BSA = 0.007184 × 94.5^0.425 × 185^0.725
BSA = 2.15 m².
Now, we can use the physician's order to find the daily dose and the total dose of Platinol for this patient. The daily dose is:.
Daily dose = 20 mg/m²/day × BSA Daily dose = 20 mg/m²/day × 2.15 m² Daily dose = 43 mg/day.
The total dose for 5 days is:.
Total dose = Daily dose × Number of days Total dose = 43 mg/day × 5 days
Total dose = 215 mg.
Therefore, the patient's dose of Platinol would be 215 mg in total, or 43 mg per day for 5 days.
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Related Questions
Correct Answer is A
Explanation
To calculate the time it will take to finish the infusion, we can use the formula:
Time = Volume / Rate
Plugging in the given values, we get:
Time = 1.5 L / 75 mL/hr Converting 1.5 L to mL, we get:
Time = 1500 mL / 75 mL/hr Simplifying, we get:
Time = 20 hours
Therefore, it will take 20 hours to finish the infusion at the current rate.
Correct Answer is D
Explanation
First, we need to calculate the total dose of esmolol required per minute: Total dose = Weight x Dose x 60 minutes
Total dose = 65 kg x 200 mcg/kg/min x 60 minutes Total dose = 780,000 mcg/min
Next, we need to convert the dose to milligrams (mg):
780,000 mcg/min = 780 mg/min
The concentration of the esmolol solution is 2,500 mg in 250 mL or 10 mg/mL. To deliver 780 mg/min at a concentration of 10 mg/mL, we need to infuse: Infusion rate = Total dose / Concentration
Infusion rate = 780 mg/min / 10 mg/mL Infusion rate = 78 mL/min
Rounding to the nearest whole number, the answer is D. 78 mL/hr.
Therefore, the nurse should calculate an infusion rate of 78 mL/hr to deliver the required dose of esmolol to the patient.
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