A patient with neuroleptic malignant syndrome has been prescribed dantrolene 1.5 mg/kg IV. The patient weighs 132 pounds.

The label on the 250 mg vial reads, “Reconstitute with 5 mL sterile water for injection, USP. Reconstitution yields 50 mg/mL.”. How many mL should the nurse administer?

Choice A rationale
The neonatal screening test, which includes thyroxine (T4) and thyroid-stimulating hormone (TSH) levels, is a routine blood test required by law to screen for metabolic deficiencies. This test helps diagnose thyroid conditions. T4 is a thyroid hormone, and too much or too little of it can indicate an issue with the thyroid. TSH is a hormone your pituitary gland makes. It stimulates your thyroid to produce T4 and T3 (triiodothyronine) hormones. A TSH test is the best way to initially assess thyroid function. In fact, T4 tests more accurately reflect thyroid function when combined with a TSH test. Measuring T4 levels might not be necessary in all thyroid conditions. Other names for a T4 test include: Free thyroxine, Total T4 concentration, Thyroxine screen, Free T4 concentration, Free T4 index (FTI)1.

Choice B rationale
While the T4 and TSH tests can help diagnose thyroid conditions, they are not specifically used to determine dosages for thyroid replacement therapy. The dosage of thyroid replacement therapy is usually determined by a healthcare provider based on the patient’s medical condition, weight, age, laboratory test results, and response to treatment.
Choice C rationale
The neonatal screening test is not specifically used for the early detection of intellectual disabilities. However, it is important to note that untreated congenital hypothyroidism can lead to intellectual disabilities. Therefore, early detection and treatment of hypothyroidism generally result in normal growth and development.
Choice D rationale
While these laboratory values can provide data about the thyroid function of the newborn, they do not directly provide data to anticipate delays in growth and development. However, untreated congenital hypothyroidism can lead to growth and developmental delays. Therefore, early detection and treatment of hypothyroidism generally result in normal growth and development.

Choice A rationale
Replacing the IV site with a smaller gauge is not the most appropriate intervention in this situation. The client’s confusion and picking at the dressing and tape are likely due to the dementia and increased confusion at night, known as “sundowning”. While a smaller gauge might be less noticeable to the client, it does not address the primary issue of the client’s confusion and restlessness at night.

Choice B rationale
Applying soft bilateral wrist restraints might be considered in some situations to prevent a confused client from removing necessary medical devices. However, restraints should be a last resort after all other interventions have been tried because they can increase agitation and confusion, and they pose a risk for injury.
Choice C rationale
Redressing the abdominal incision is the correct choice. The dressing is no longer occlusive, which means it’s not providing a proper barrier to bacteria. This could lead to an infection in the surgical site. The nurse should clean the area and apply a new sterile dressing.
Additionally, the nurse should continue to monitor the client’s behavior and implement interventions to reduce confusion and restlessness, such as reorienting the client and providing a quiet and calm environment.
Choice D rationale
Leaving the lights on in the room at night can actually increase confusion and agitation in clients with dementia. It can disrupt the client’s sleep-wake cycle and make “sundowning” worse. Therefore, this is not the most appropriate intervention.