A patient who has just been prescribed an incretin enhancer, asks the nurse how it works. The nurse informs the patient that these types of medications:
Increase insulin production by the pancreas
Increase insulin secretion from the pancreas
Decrease the amount of glucagon produced by the pancreas
Decrease the uptake of glucose by the body's cells
The Correct Answer is B
A. Increase insulin production by the pancreas: This is incorrect because incretin enhancers don't increase the production of insulin itself but rather enhance the secretion of insulin in response to meals.
B. Increase insulin secretion from the pancreas: This is correct. Incretin enhancers (e.g., DPP-4 inhibitors or GLP-1 receptor agonists) work by amplifying the effect of incretins, which are hormones that increase insulin secretion in response to meals.
C. Decrease the amount of glucagon produced by the pancreas: This is partly true but not the primary mechanism. Incretins do reduce glucagon release, which helps lower blood glucose, but the main action is to increase insulin secretion.
D. Decrease the uptake of glucose by the body's cells: This is incorrect. Incretin enhancers do not work by decreasing glucose uptake by cells; rather, they enhance insulin secretion which in turn helps cells to uptake glucose.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["Glucagon"]
Explanation
The Islets of Langerhans in the pancreas produce two main hormones: insulin and glucagon. Insulin helps regulate blood sugar by lowering it, while glucagon acts conversely to raise blood sugar levels.
Correct Answer is D
Explanation
A. The patient may choke: This is not the primary concern for extended-release medications like metformin (Glucophage XL). While choking is a risk with any pill, it's not specific to the need for avoiding crushing or chewing extended-release formulations.
B. It would cause blood glucose levels to rise too rapidly: Crushing or chewing the medication would not cause blood glucose levels to rise rapidly. Instead, it could lead to a more rapid release and absorption of the drug, which might lower blood glucose too quickly, potentially leading to hypoglycemia.
C. Irritation of the oral mucosa may occur: While irritation of the oral mucosa could be a concern with some medications, it is not the primary reason for avoiding the crushing or chewing of extended-release formulations like Glucophage XL.
D. The effect of the medication may be changed: Crushing or chewing an extended-release tablet disrupts its formulation. Glucophage XL is designed to release metformin slowly over time. If the tablet is crushed or chewed, it can result in the entire dose being released at once, which can alter the intended pharmacokinetics and pharmacodynamics of the drug. This could lead to a higher risk of side effects and a loss of the extended-release benefit, ultimately changing the medication's effect and possibly leading to issues like hypoglycemia or gastrointestinal side effects.
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