Choice A rationale
The patient is receiving a nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) for HIV
treatment and reports experiencing malaise, fatigue, and anorexia. These symptoms, along
with the observed increased respiratory rate, could be indicative of liver toxicity, a known
potential side effect of NRTIs. Therefore, reviewing liver function tests would be most
important in this case.
Choice B rationale
While arterial blood gases can provide valuable information about a patient’s respiratory
status, they may not be the most relevant in this context. The patient’s symptoms and the side
effect profile of NRTIs suggest that liver function may be a more pressing concern.

Choice C rationale
A complete blood count (CBC) can provide a broad overview of a patient’s general health, but it
may not provide the specific information needed to assess the patient’s current symptoms and
potential medication side effects.
Choice D rationale
A basic metabolic panel can provide information about a patient’s kidney function, electrolyte
levels, and blood sugar levels, among other things. However, given the patient’s symptoms and
medication regimen, liver function tests may be more relevant.

Choice A rationale
Heart rate is an important vital sign to monitor in patients, but it is not the primary outcome
data to prioritize when administering a 20% mannitol intravenous (IV) solution. Mannitol is a diuretic that works by increasing the amount of urine produced. Therefore, while heart rate can be affected by fluid balance changes, it is not the most directly relevant outcome to monitor in this context.
Choice B rationale
Ankle circumference could be an indicator of peripheral edema, which might suggest fluid
overload or poor kidney function. However, in the context of mannitol administration, which is a diuretic and would be expected to decrease fluid overload, ankle circumference is not the primary outcome to monitor.
Choice C rationale
Urinary output is the correct answer. Mannitol is an osmotic diuretic that increases urine
production. It is used to reduce intracranial and intraocular pressure by drawing water out of tissues and into the bloodstream, from where it can be excreted by the kidneys. Therefore, urinary output is the most direct measure of its effectiveness and is the key outcome that should be monitored.
Choice D rationale
Dietary intake is always important to monitor in patients, especially those receiving IV
therapy, as it can impact electrolyte balance and overall health status. However, it is not the primary outcome to monitor when administering mannitol.