A patient has fallen and injured her knee.
It is not fractured, but there is considerable swelling and pain.
She asks which over-the-counter analgesic would be best to take for her discomfort.
The nurse tells her that one with NSAID properties would be best.
Which would it be best to take?

Choice A rationale:

Sleep influences memory. During the different stages of sleep, particularly during deep sleep (slow-wave sleep and rapid eye movement sleep), the consolidation of memories occurs. This means that sleep plays a critical role in memory function.

Choice B rationale:

Sleep influences mood. A lack of sleep or disrupted sleep patterns can lead to mood disturbances, including irritability, anxiety, and depression. Adequate sleep is essential for maintaining a stable and positive mood.

Choice C rationale:

Sleep influences cognitive function. Sleep is crucial for cognitive processes such as attention, problem-solving, and decision-making. Sleep deprivation can impair cognitive function, leading to reduced alertness and cognitive performance.

Choice D rationale:

Sleep influences the secretion of various hormones. Sleep plays a significant role in regulating hormones such as growth hormone, cortisol, and melatonin. Disruptions in sleep can lead to imbalances in these hormones, affecting various physiological processes.

Choice E rationale:

Sleep influences immune function. Adequate sleep is essential for a healthy immune system. During sleep, the immune system is actively engaged in repairing and protecting the body. Sleep deprivation can weaken the immune response, making individuals more susceptible to infections.

Choice F rationale:

Sleep influences body temperature. The body's core temperature fluctuates during the sleep-wake cycle, with the lowest point typically occurring during the night when we are asleep. This temperature regulation is essential for sleep quality and overall health.

Choice G rationale:

Sleep influences renal function. Sleep has an impact on various physiological processes, including renal function. The kidneys play a role in regulating blood pressure and electrolyte balance, which can be influenced by sleep patterns.

Choice A rationale:

Indomethacin (Indocin) is a nonsteroidal anti-inflammatory medication (NSAID). It is commonly used to reduce inflammation and relieve pain, making it a suitable choice for pain management in conditions where inflammation plays a role, such as arthritis or musculoskeletal injuries.

Choice B rationale:

Indomethacin is not typically categorized as an adjuvant analgesic. Adjuvant analgesics are medications that are not primarily designed for pain relief but may enhance the effects of analgesics when used in combination.

Choice C rationale:

Indomethacin is not a COX-2 inhibitor. COX-2 inhibitors are a specific class of NSAIDs that target the COX-2 enzyme while sparing COX-1. Indomethacin is a traditional NSAID that inhibits both COX-1 and COX-2.

Choice D rationale:

Indomethacin is not a narcotic analgesic. Narcotic analgesics, also known as opioids, are a separate class of medications used for the management of moderate to severe pain. Indomethacin does not belong to this class and has a different mechanism of action.