A patient diagnosed with schizophrenia had an exacerbation of hallucinations and delusions related to medication non-adherence and was hospitalized for 10 days. The patient is stabilized and discharge is planned. The patient’s family is concerned that the patient’s symptoms will return after discharge. Acting as an advocate for the patient’s rights, the nurse’s best response is:

Choice A reason: Decreasing dopamine is used for disorders like schizophrenia, where excess mesolimbic dopamine causes hallucinations. Memory difficulties, often linked to Alzheimer’s, involve cholinergic deficits, not dopamine excess. Reducing dopamine could worsen cognition by disrupting reward and attention pathways, making this approach scientifically inappropriate for memory issues.

Choice B reason: Inhibiting GABA production is irrelevant for memory. GABA regulates neural inhibition, and its reduction could increase excitability, worsening conditions like seizures. Memory deficits, particularly in dementia, stem from reduced acetylcholine in the hippocampus, not GABA, making this option misaligned with the neurobiology of memory impairment.

Choice C reason: Preventing acetylcholine destruction, via cholinesterase inhibitors, enhances cholinergic activity in the hippocampus and cortex, critical for memory in conditions like Alzheimer’s. Low acetylcholine levels impair neural signaling, causing memory deficits. This approach directly addresses the neurochemical basis of memory difficulties, making it scientifically appropriate for treatment.

Choice D reason: Increasing dopamine sensitivity is relevant for disorders like Parkinson’s, not memory deficits. Dopamine affects motivation and movement, not memory, which relies on acetylcholine in the hippocampus. Enhancing dopamine could disrupt cognitive balance, worsening memory without addressing the cholinergic deficits central to memory impairment.

Choice A reason: Minimizing suicide as drastic dismisses the patient’s emotional pain, linked to serotonin deficits and amygdala hyperactivity in depression. This lacks empathy, risking alienation and worsening despair, as it fails to acknowledge the neurobiological severity of suicidal ideation, making it inappropriate.

Choice B reason: Acknowledging intense upset validates the patient’s emotional state, reflecting serotonin-driven despair in suicide attempts. Empathy, engaging mirror neurons, fosters trust and reduces isolation, aligning with therapeutic principles to support neurobiological stabilization and emotional recovery in psychiatric care.

Choice C reason: Offering to solve problems focuses on solutions, not empathy. Suicidal ideation, tied to prefrontal cortex dysfunction, requires emotional validation first. This statement risks dismissing feelings, reducing therapeutic connection, and is less effective than acknowledging the patient’s emotional distress.

Choice D reason: Expressing personal sadness shifts focus to the nurse’s feelings, not the patient’s. Empathy requires reflecting the patient’s emotional state, like despair from serotonin imbalances, to build rapport. This statement, while sympathetic, is less empathic, making it incorrect for demonstrating true empathy.