A nurse working in an urgent care clinic is collecting data from a client who takes montelukast.
Which of the following is an expected therapeutic effect of this medication?

Choice A rationale:

Dry mouth is a common side effect of diphenhydramine. Diphenhydramine is an antihistamine that is often used to treat allergies, insomnia, and symptoms of the common cold. It works by blocking the effects of histamine, a substance in the body that causes allergy symptoms. One of the effects of histamine is increased salivation, so when diphenhydramine blocks this effect, it can lead to dry mouth.

Choice B rationale:

Nausea is also a common side effect of diphenhydramine. This can occur because diphenhydramine can slow down the emptying of the stomach, leading to feelings of nausea. Additionally, diphenhydramine can affect the vestibular system in the inner ear, which can also lead to feelings of nausea.

Choice C rationale:

Agitation is considered an idiosyncratic reaction to diphenhydramine. An idiosyncratic reaction is an unusual or unexpected reaction to a drug that is not related to the usual pharmacological action of the drug. While diphenhydramine is typically used for its sedative effects, in some cases it can cause paradoxical central nervous system stimulation, leading to agitation.

Choice D rationale:

Dizziness is another common side effect of diphenhydramine. This occurs because diphenhydramine can affect the vestibular system in the inner ear, which plays a key role in maintaining balance. When this system is affected, it can lead to feelings of dizziness.

Choice A rationale:

“You must rinse your mouth out after each dose.” This is incorrect. Rinsing the mouth after each dose is usually recommended for inhaled corticosteroids, not oral prednisone.

Choice B rationale:

“You should take this medication on an empty stomach.” This is incorrect. Prednisone should be taken with food to prevent stomach upset.

Choice C rationale:

“You should take a calcium supplement while taking this medication.” This is correct because long-term use of prednisone can lead to bone loss (osteoporosis) Taking a calcium supplement can help protect bone health.

Choice D rationale:

“You can expect some weight loss with this medication.” This is incorrect. Weight gain, not weight loss, is a common side effect of long-term prednisone use.