A nurse is reviewing the medication list of a patient with end-stage renal disease (ESRD) who is receiving hemodialysis. The nurse knows that certain medications are used to prevent complications of this disease. Which of the following medications would the nurse question as part of routine therapy for preventing complications of ESRD?

Antihypertensive medications

Antidiuretic hormone (ADH)

Erythrocyte-stimulating agents

Phosphate binders

Answer and Explanation

The Correct Answer is B

Choice A reason: Antihypertensives are routinely used in ESRD to manage hypertension caused by fluid overload and renin-angiotensin system dysregulation. Controlling blood pressure prevents cardiovascular complications like heart failure or stroke, which are common in ESRD due to chronic volume and pressure overload, making this medication appropriate.

Choice B reason: ADH is not used in ESRD, as it promotes water reabsorption, worsening fluid overload in anuric patients. ESRD patients rely on dialysis for fluid balance, and ADH could exacerbate hypertension or pulmonary edema. Its use is more relevant in conditions like diabetes insipidus, not renal failure.

Choice C reason: Erythrocyte-stimulating agents, like erythropoietin, are standard in ESRD to treat anemia caused by reduced erythropoietin production by failing kidneys. These agents stimulate red blood cell production, improving oxygen delivery and reducing fatigue, making them essential for managing ESRD-related anemia and improving quality of life.

Choice D reason: Phosphate binders are used in ESRD to manage hyperphosphatemia by binding dietary phosphate in the gut, preventing its absorption. This reduces the risk of vascular calcification and secondary hyperparathyroidism, common complications in ESRD due to impaired phosphate excretion, making these medications a standard part of therapy.

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Free Nursing Study Resources

Correct Answer is ["2.5"]

Explanation

Step 1 is identify the total dose ordered
10 mg

Step 2 is identify the concentration available
4 mg per mL

Step 3 is divide the ordered dose by the concentration per mL
(10 ÷ 4) = 2.5

Result = 2.5 mL

A. A 70-year-old client with a BMI of 30 and a history of hypertension B. A 64-year-old client with a history of vascular disorders C. A 50-year-old client with poorly controlled diabetes mellitus D. A 60-year-old client with chronic obstructive pulmonary disease E. A 60-year-old client with a recent episode of dehydration due to gastroenteritis

Correct Answer is ["A","B","C"]

Explanation

Choice A reason: Hypertension and obesity (BMI 30) are major risk factors for ESRD. Chronic hypertension damages renal vasculature, reducing glomerular filtration over time. Obesity exacerbates hypertension and promotes glomerulosclerosis, leading to progressive kidney damage. This combination significantly increases the risk of developing ESRD through sustained renal injury.

Choice B reason: Vascular disorders, such as atherosclerosis, impair renal blood flow, causing ischemic nephropathy. Chronic reduced perfusion damages nephrons, leading to progressive renal failure. Vascular diseases also contribute to hypertension, further stressing kidneys. This client’s history indicates a high risk for ESRD due to ongoing vascular compromise affecting renal function.

Choice C reason: Poorly controlled diabetes mellitus causes diabetic nephropathy, a leading cause of ESRD. Chronic hyperglycemia damages glomerular capillaries, leading to proteinuria and declining kidney function. Sustained high glucose levels accelerate nephron loss, making this client at high risk for ESRD due to irreversible renal damage from diabetes.

Choice D reason: Chronic obstructive pulmonary disease (COPD) primarily affects the lungs, not the kidneys. While hypoxia or medications like corticosteroids may indirectly stress kidneys, COPD is not a direct risk factor for ESRD. Renal damage requires specific insults like hypertension or diabetes, making this client less likely to develop ESRD.

Choice E reason: A recent dehydration episode from gastroenteritis can cause acute kidney injury but is reversible with treatment. It is not a chronic condition leading to ESRD unless recurrent or combined with other risk factors like diabetes or hypertension. This isolated event poses a lower risk for ESRD development.

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Naxlex Comprehensive Predictor Exams

Morphine sulfate 10 mg IV is prescribed. Available 4 mg/mL How many mL be given?

Correct Answer is ["2.5"]

Explanation

The nurse is receiving the morning report on four clients on a medical-surgical unit. Based on the information provided, which clients are at greatest risk for developing end-stage renal disease (ESRD)? (Select all that apply)

Correct Answer is ["A","B","C"]

Explanation

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