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A nurse is reinforcing teaching with a group of nurses about the administration of nitroglycerin. Which of the following routes of administration provides the most rapid onset for the client?

Suspended release

Transdermal patch

Topical ointment

Sublingual

Answer and Explanation

The Correct Answer is D

A. Suspended release formulations typically have a slower onset of action compared to sublingual administration.

B. Transdermal patches provide a slow, continuous release of nitroglycerin and do not offer rapid onset.

C. Topical ointments have a slower onset of action compared to sublingual administration.

D. Sublingual administration of nitroglycerin provides the most rapid onset of action due to direct absorption through the oral mucosa.

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Correct Answer is C

Explanation

A. Organic nitrates do not increase contractility and heart rate; they typically decrease myocardial oxygen demand.

B. Organic nitrates do not slow heart rate or decrease contractility of the heart.

C. The mechanism of action of organic nitrates in the treatment of angina is the relaxation of arterial and venous smooth muscle, leading to vasodilation and decreased myocardial oxygen demand.

D. Organic nitrates do not increase peripheral resistance; they typically cause vasodilation.

A. The most common side effect of nitroglycerin is a headache B. Nitroglycerin does not cause a headache C. The client will not have a headache if the nitroglycerin is taken with a high-fat meal D. A headache indicates a serious allergic reaction to nitroglycerin

Correct Answer is A

Explanation

Explanation:

A. Headache is a common side effect of nitroglycerin due to vasodilation and can often be managed with continued use.

B. Nitroglycerin is known to cause headaches as a common side effect.

C. Taking nitroglycerin with a high-fat meal is not likely to prevent headaches; it may, in fact, delay absorption and onset of action.

D. A headache alone is not indicative of a serious allergic reaction to nitroglycerin; other symptoms would typically be present.

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A nurse is reinforcing teaching with a group of nurses about the administration of nitroglycerin. Which of the following routes of administration provides the most rapid onset for the client?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

In the treatment of angina, the mechanism of action of an organic nitrate is:

Correct Answer is C

Explanation

A client taking nitroglycerin (Nitrostat) complains of a headache. Which conclusion is most appropriate by the nurse?

Correct Answer is A

Explanation

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