A nurse is providing education to a parent of a child newly diagnosed with cystic fibrosis (CF).
The parent asks, "How is CF inherited?" Which of the following statements by the nurse is correct?
"CF is inherited through an X-linked dominant pattern.”
"CF is an autosomal recessive genetic disorder.”
"CF is inherited when a child inherits a defective CFTR gene from one parent.”
"CF is solely caused by the deletion of phenylalanine at position 508 (F508del).”
The Correct Answer is B
"CF is an autosomal recessive genetic disorder.”.
Choice A rationale:
CF is not inherited through an X-linked dominant pattern.
X-linked inheritance involves genes located on the X chromosome, and CF is not linked to this type of inheritance.
Choice C rationale:
CF is not solely related to inheriting a defective CFTR gene from one parent.
While inheriting a mutated CFTR gene is a factor, CF is an autosomal recessive disorder, meaning it requires mutations in both copies of the CFTR gene (one from each parent) for the disease to manifest.
Choice D rationale:
CF is not solely caused by the deletion of phenylalanine at position 508 (F508del).
While this mutation is one of the most common causes of CF, it is not the only genetic variation associated with the disease.
CF can result from various mutations in the CFTR gene.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale:
Increased lung compliance is not a common respiratory complication of cystic fibrosis (CF).
CF is characterized by the production of thick and sticky mucus in the airways, which leads to decreased lung compliance.
This thick mucus obstructs the airways, making it difficult for the child to breathe.
Choice B rationale:
Decreased breath sounds are a common respiratory complication of CF.
The thick and sticky mucus produced in CF can block the airways, leading to decreased breath sounds upon auscultation.
This can result in impaired air movement and reduced ventilation in affected areas of the lungs.
Choice C rationale:
Normal oxygen saturation is not typically a common respiratory complication of CF.
CF often leads to decreased oxygen saturation due to the impaired lung function caused by mucus buildup and recurrent infections.
Choice D rationale:
Clear and thin sputum production is not a common finding in CF.
CF is associated with the production of thick and sticky mucus, leading to productive cough with thick, tenacious sputum.
Correct Answer is C
Explanation
Choice A rationale:
"CF leads to excessive production of digestive enzymes in the pancreas.”.
This statement is not accurate.
In fact, CF impairs the production of digestive enzymes in the pancreas.
The thick mucus produced in CF can block the pancreatic ducts, preventing the release of enzymes needed for proper digestion.
Choice B rationale:
"CF has no impact on the function of the pancreas.”.
This statement is incorrect.
CF significantly affects the function of the pancreas by obstructing the pancreatic ducts and impairing the production of digestive enzymes.
Choice C rationale:
"CF impairs the pancreas's ability to produce digestive enzymes.”.
This statement is accurate.
CF causes the thick and sticky mucus to accumulate in the pancreas, obstructing the release of digestive enzymes, which are essential for the digestion of fats and proteins.
Choice D rationale:
"CF causes the pancreas to produce excessive insulin.”.
This statement is not correct.
CF does not lead to excessive insulin production.
Instead, it primarily affects the production of digestive enzymes and can lead to issues related to fat malabsorption.
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