A nurse is preparing to administer lidocaine via continuous IV infusion at 4 mg/min. Available is lidocaine 2 g dextrose 5% in water 500 mL. The nurse should set the IV pump to deliver how many mL/hr?
(Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)

Choice A Reason:
Bone loss is correct. Prednisone, a corticosteroid, can lead to decreased bone density (osteoporosis) over extended periods of use, particularly in older adults. This adverse effect increases the risk of fractures and bone-related issues due to the drug's impact on bone health and calcium absorption.
Choice B Reason:
Liver toxicity is incorrect. While prednisone can affect liver function tests in some cases, it is less commonly associated with significant liver toxicity compared to other medications. However, liver function should be monitored during prolonged use.
Choice C Reason:
Hemolytic anemia is incorrect. Prednisone is not typically associated with causing hemolytic anemia as an adverse effect.
Choice D Reason:
Hypoglycemia is not a common adverse effect associated with prednisone use. In fact, prednisone can elevate blood sugar levels and may lead to hyperglycemia or exacerbate diabetes in susceptible individuals.

Choice A Reason:
"I will check the client's INR before administering the heparin." is incorrect. Checking the client's INR (International Normalized Ratio) is essential, but it's more applicable for monitoring anticoagulants like warfarin, not heparin. Heparin's effect is typically monitored via activated partial thromboplastin time (aPTT) or anti-Xa levels, not INR.
Choice B Reason:
"I will aspirate before administering the heparin." Is incorrect. Aspirating before administering heparin injections is not necessary because the medication is given subcutaneously or intravenously and not into a blood vessel.
Choice C Reason:
"I will massage the site after injecting the heparin." Is incorrect. Massaging the site after injecting heparin could increase the risk of bruising or hematoma formation at the injection site. It's generally advised to avoid massaging the area after a heparin injection to prevent tissue trauma.
Choice D Reason:
"I will apply pressure for 1 minute after the injection." Is correct. Applying pressure to the injection site for about a minute after administering heparin helps reduce the risk of bleeding or hematoma formation, especially with subcutaneous injections. This practice aids in minimizing bleeding at the injection site.