A nurse is planning care for a client who has multiple sclerosis and is receiving methylprednisolone. Which of the following adverse effects should the nurse anticipate? (Select all that apply.)
Bladder spasms
Hypotension
Delayed wound healing
Hirsutism
Hyperglycemia
Correct Answer : C,D,E
Choice A Reason:
Bladder spasms are not commonly reported as adverse effects of methylprednisolone. However, bladder dysfunction can occur in individuals with multiple sclerosis due to the disease process itself, but it is not specifically related to corticosteroid therapy.
Choice B Reason:
Hypotension is not a common adverse effect of methylprednisolone. In fact, corticosteroids can often lead to fluid retention and sodium retention, which can contribute to hypertension rather than hypotension.
Choice C Reason:
Delayed wound healing is correct. Corticosteroids can impair the body's ability to heal wounds by suppressing the inflammatory response and collagen synthesis. Therefore, clients receiving methylprednisolone may experience delayed wound healing, which can be problematic, especially in individuals with pre-existing wounds or undergoing surgical procedures.
Choice D Reason:
Hirsutism (excessive hair growth, especially in women) can occur with long-term corticosteroid use due to the effect of steroids on hair follicles. It is a possible adverse effect of methylprednisolone.
Choice E Reason:
Hyperglycemia is correct. Corticosteroids can increase blood glucose levels by promoting gluconeogenesis, reducing glucose uptake by tissues, and inducing insulin resistance. Clients receiving methylprednisolone may develop hyperglycemia, which can be particularly concerning for individuals with diabetes or those at risk of developing diabetes.

Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
"The nerves just go to sleep when I lie down because no message gets from my brain to the spinal cord." is incorrect because it does not accurately describe the mechanism of peripheral neuropathy. Peripheral neuropathy in diabetes is not simply the nerves "going to sleep" due to lack of communication between the brain and spinal cord.
Choice B Reason:
"The nerve damage may occur for unknown reasons in any individual" is incorrect because while the exact cause of peripheral neuropathy may not always be known, in the context of diabetes mellitus, the link between elevated blood sugar levels and nerve damage is well-established.
Choice C Reason:
"The older I get, there is less blood flowing to my feet. “is incorrect because while decreased blood flow (ischemia) can contribute to peripheral neuropathy in some cases, the primary mechanism in diabetic neuropathy is nerve damage due to hyperglycemia rather than reduced blood flow.
Choice D Reason:
"The elevated blood sugar from my diabetes can cause underlying nerve damage." Peripheral neuropathy is a common complication of diabetes mellitus, particularly when the condition is uncontrolled. Elevated blood sugar levels over time can lead to damage to the nerves, especially those in the feet and legs. This damage can result in symptoms such as numbness, tingling, burning sensations, or pain in the affected areas.
Correct Answer is D
Explanation
Choice A Reason:
Osteoporosis is inappropriate. Chronic respiratory acidosis can lead to osteoporosis over time due to several factors, including chronic hypoxemia, which can affect bone metabolism and lead to bone loss.
Choice B Reason:
Polyuria is inappropriate. Polyuria, or increased urination, is not typically associated with chronic respiratory acidosis. In fact, respiratory acidosis tends to cause retention of bicarbonate ions, which can lead to compensatory metabolic alkalosis and decreased urine output.
Choice C Reason:
Anxiety and depression is inappropriate. Chronic respiratory acidosis can lead to symptoms such as lethargy, confusion, and decreased mental acuity due to the effects of elevated CO2 levels on the central nervous system. While anxiety and depression are not direct consequences of chronic respiratory acidosis, individuals with COPD may experience anxiety and depression as a result of their chronic respiratory condition.
Choice D Reason:
Delirium is correct. Delirium, characterized by an acute change in mental status, confusion, and altered consciousness, can occur in severe cases of chronic respiratory acidosis, especially during acute exacerbations. Elevated CO2 levels can affect brain function and lead to symptoms of delirium.
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