A nurse is planning care for a client who has multiple sclerosis and is receiving methylprednisolone. Which of the following adverse effects should the nurse anticipate? (Select all that apply.)

Choice A Reason:

Bladder spasms are not commonly reported as adverse effects of methylprednisolone. However, bladder dysfunction can occur in individuals with multiple sclerosis due to the disease process itself, but it is not specifically related to corticosteroid therapy.

Choice B Reason:

Hypotension is not a common adverse effect of methylprednisolone. In fact, corticosteroids can often lead to fluid retention and sodium retention, which can contribute to hypertension rather than hypotension.

Choice C Reason:

Delayed wound healing is correct. Corticosteroids can impair the body's ability to heal wounds by suppressing the inflammatory response and collagen synthesis. Therefore, clients receiving methylprednisolone may experience delayed wound healing, which can be problematic, especially in individuals with pre-existing wounds or undergoing surgical procedures.

Choice D Reason:

Hirsutism (excessive hair growth, especially in women) can occur with long-term corticosteroid use due to the effect of steroids on hair follicles. It is a possible adverse effect of methylprednisolone.

Choice E Reason:

Hyperglycemia is correct. Corticosteroids can increase blood glucose levels by promoting gluconeogenesis, reducing glucose uptake by tissues, and inducing insulin resistance. Clients receiving methylprednisolone may develop hyperglycemia, which can be particularly concerning for individuals with diabetes or those at risk of developing diabetes.

Choice A Reason:

"When did you have your last physical?": This question is relevant to assess the client's overall health status and identify any potential comorbidities or health conditions that may be associated with Parkinson's disease. However, it is not as crucial as asking about family history, which directly addresses the client's potential genetic predisposition to Parkinson's disease.

Choice B Reason:

"Do you have any family members with Parkinson's disease?" Parkinson's disease can have both genetic and environmental factors contributing to its development. While the exact cause of Parkinson's disease is not fully understood, having a family history of the condition is a significant risk factor. Individuals with first-degree relatives (parents, siblings, or children) who have Parkinson's disease have an increased risk of developing the condition themselves.

Choice C Reason:

"What kind of work do you do?": This question aims to gather information about the client's occupational history and potential exposure to environmental toxins or factors that may be associated with Parkinson's disease. Certain occupations or exposures to pesticides, herbicides, heavy metals, or other toxins have been linked to an increased risk of Parkinson's disease. While occupational history is important, it is not as directly relevant to assessing the client's risk factors as asking about family history.

Choice D Reason:

"How much coffee do you drink every day?": Research has suggested that caffeine consumption may be associated with a reduced risk of Parkinson's disease or may potentially delay its onset. However, the evidence is not definitive, and the relationship between caffeine intake and Parkinson's disease is still not fully understood. While caffeine consumption may be a relevant factor to explore, especially if the client has a high intake of coffee, it is not as critical as inquiring about family history, which directly addresses genetic predisposition to Parkinson's disease.