Choice A rationale:
Contact inhibition is a normal mechanism that regulates cell growth. When normal cells come into contact with each other, they stop growing. This prevents uncontrolled growth and the formation of tumors.
Benign tumor cells do not typically lose contact inhibition. They still respond to contact signals from neighboring cells and stop growing when they come into contact with each other.
However, they may grow in an uncontrolled manner due to other factors, such as mutations in genes that regulate cell growth.
Choice C rationale:
Invasion is a characteristic of malignant (cancerous) tumors, not benign tumors. Malignant tumors have the ability to invade surrounding tissues and spread to other parts of the body.
Benign tumors, on the other hand, are localized and do not invade surrounding tissues. They may grow and compress nearby tissues, but they do not spread.
Choice D rationale:
Anaplasia is a term used to describe the loss of differentiation of cells in a tumor. This means that the cells no longer resemble the normal cells from which they originated.
Anaplasia is a characteristic of malignant tumors, not benign tumors. Benign tumor cells typically retain some of the characteristics of the parent cells.

Choice A rationale:
While PICCs are typically intended for shorter-term use (up to 12 weeks), the fact that a PICC has been in place for 4 weeks is not, in itself, an immediate cause for concern. Regular assessment of the catheter and site is crucial, but the duration of placement alone does not warrant immediate attention.
Choice B rationale:
While it's generally recommended to change PICC dressings every 7 days, a dressing that is 3 days old is not an immediate emergency. The nurse should prioritize changing the dressing as soon as possible, but it does not require the same level of urgency as other potential complications.
Choice C rationale:
A missing securement device is a concern because it can increase the risk of catheter dislodgement or migration. However, it does not necessarily indicate an immediate threat to the patient's well-being. The nurse should promptly address the missing securement device, but it would not be the most pressing issue compared to swelling in the extremity.
Choice D rationale:
Swelling in the upper extremity where the PICC is located is a significant finding that demands immediate attention. It can be a sign of several serious complications, including:
Thrombosis: A blood clot within the vein, which can obstruct blood flow and lead to pain, swelling, and potentially more severe consequences like deep vein thrombosis (DVT) or pulmonary embolism (PE).
Infection: Inflammation and infection at the insertion site or within the bloodstream, which can cause swelling, redness, warmth, and pain. If left untreated, infection can progress to sepsis, a life-threatening condition.
Phlebitis: Inflammation of the vein, which can cause pain, redness, and swelling along the vein.
Infiltration: Leakage of fluids or medications into the surrounding tissue, leading to swelling and discomfort.
Prompt action is crucial in these cases to prevent further complications and ensure patient safety. The nurse should immediately notify the appropriate healthcare provider, initiate necessary interventions, and closely monitor the patient's condition.