A nurse is conducting a research study to compare the effects of two different pain medications on postoperative patients.
The nurse randomly assigns the patients to either receive medication A or medication B. Which of the following is the best way to ensure that the study is valid and reliable?
Use a large sample size and a standardized procedure for administering the medications.
Use a placebo group and a double-blind technique for giving the medications.
Use a matched-pairs design and a crossover technique for switching the medications.
Use a convenience sample and a pretest-posttest design for measuring the pain levels.
The Correct Answer is B
Using a placebo group and a double-blind technique for giving the medications is the best way to ensure that the study is valid and reliable.
A placebo group helps control for the placebo effect, which can influence the results of a study.
A double-blind technique means that neither the patients nor the researchers know which medication is being given, reducing bias.
Choice A is not the best answer because while a large sample size and standardized procedure can increase reliability, they do not address validity.
Choice C is not the best answer because a matched-pairs design and crossover technique are useful for reducing variability but do not address validity.
Choice D is not the best answer because a convenience sample may not be representative and a pretest-posttest design does not control for extraneous variables.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Granzymes are a family of serine proteases that are stored in and secreted from the cytotoxic granules of cytotoxic T lymphocytes (CTL) and natural killer (NK) cells.
They work in synergy with perforin, a pore-forming toxin, to induce apoptosis in target cells.
Perforin is necessary for the delivery of granzyme B to the target cell cytosol where caspase-dependent and -independent pathways to apoptosis are activated.
Perforins (choice A) are pore-forming toxins that work in synergy with granzymes to induce apoptosis in target cells.
Cytokines (choice B) are signaling molecules that regulate immune responses but do not directly induce apoptosis in target cells.
Interferons (choice D) are a type of cytokine that play a role in immune responses but do not directly induce apoptosis in target cells.
Correct Answer is A
Explanation
During the menstrual cycle, the corpus luteum in the ovary produces progesterone to prepare the endometrium for potential implantation.
Choice B is incorrect because fimbriae are finger-like projections at the end of the fallopian tubes that help guide the egg into the tube.
Choice C is incorrect because a follicle is a sac in the ovary that contains an immature egg.
Choice D is incorrect because the ovarian ligament is a fibrous band of tissue that connects the ovary to the uterus.
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