A nurse is conducting a research study to compare the effects of two different pain medications on postoperative patients.
The nurse randomly assigns the patients to either receive medication A or medication B. Which of the following is the best way to ensure that the study is valid and reliable?
Use a large sample size and a standardized procedure for administering the medications.
Use a placebo group and a double-blind technique for giving the medications.
Use a matched-pairs design and a crossover technique for switching the medications.
Use a convenience sample and a pretest-posttest design for measuring the pain levels.
The Correct Answer is B
Using a placebo group and a double-blind technique for giving the medications is the best way to ensure that the study is valid and reliable.
A placebo group helps control for the placebo effect, which can influence the results of a study.
A double-blind technique means that neither the patients nor the researchers know which medication is being given, reducing bias.
Choice A is not the best answer because while a large sample size and standardized procedure can increase reliability, they do not address validity.
Choice C is not the best answer because a matched-pairs design and crossover technique are useful for reducing variability but do not address validity.
Choice D is not the best answer because a convenience sample may not be representative and a pretest-posttest design does not control for extraneous variables.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A primer is a short single-stranded DNA fragment used in certain laboratory techniques, such as the polymerase chain reaction (PCR).
In the PCR method, a pair of primers hybridizes with the sample DNA and defines the region that will be amplified.

Choice A) A short piece of double-stranded DNA that binds to the template DNA and acts as a “starter” for the polymerase is incorrect because primers are single-stranded, not double-stranded.
Choice B) A short piece of double-stranded DNA that binds to the primer and acts as a “starter” for the template is incorrect because it does not make sense for a primer to bind to itself.
Choice D) A short piece of single-stranded DNA that binds to the polymerase and acts as a “starter” for the template is incorrect because primers bind to the template DNA, not to the polymerase.
Correct Answer is A
Explanation
In a well-designed experiment, all variables apart from the treatment should be kept constant between the control group and treatment group.
This means researchers can correctly measure the entire effect of the treatment without interference from confounding variables.

Choice B) Independent variable and dependent variable is incorrect because these are not groups but rather variables.
The independent variable is manipulated by the experimenters while the dependent variable is measured to see if it changes as a result of the manipulation.
Choice C) Experimental group and non-experimental group is incorrect because a non-experimental group is not a term used in experimental design.
The correct term for the group that does not receive the treatment is control group.
Choice D) High level and low level of the independent variable is incorrect because these are levels of the independent variable, not groups.
In an experiment, there can be multiple levels of the independent variable, but they are applied to different groups (e.g. control group, treatment group).
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