A nurse is collecting data from an older adult client who is receiving ondansetron IV, has a history of diabetes mellitus and cardiac myopathy, and is receiving chemotherapy to treat cancer. For which of the following adverse effects of ondansetron should the nurse monitor? (Select all that apply)

B. Before administering any medication, especially antibiotics like amoxicillin, the nurse must assess the patient for allergies or previous adverse reactions to amoxicillin or other beta-lactam antibiotics. Allergic reactions can range from mild rashes to severe anaphylactic reactions, so it's essential to confirm the

patient's allergy status and assess for any signs or symptoms of allergic reaction before proceeding with administration.

A. Flushing the IV site with normal saline is typically not required specifically before administering IV amoxicillin unless it is part of the institution's standard practice to flush all IV lines before and after medication administration.

C. While monitoring intake and output (I&O) is important for assessing fluid balance and kidney function, it is not directly necessary before administering IV amoxicillin unless there are specific concerns related to the patient's fluid status or renal function. However, it is good practice to have a general understanding of the patient's recent fluid intake and output patterns.

D. Creatinine clearance is a measure of kidney function. Checking the latest creatinine clearance result is important for assessing renal function, especially before administering medications excreted by the kidneys. However, amoxicillin is primarily excreted by the kidneys in its unchanged form, so knowing the patient's renal function status can help in determining the appropriate dosage or adjusting the dosing interval if necessary.

B. Sucralfate should be taken on an empty stomach, at least 1 hour before meals or 2 hours after meals, to maximize its effectiveness. Food can interfere with its ability to coat the stomach lining.

A. Constipation is a common side effect of sucralfate, but it does not typically require discontinuation of the medication. Instead, clients are often advised to manage constipation with dietary fiber, fluids, and sometimes mild laxatives if necessary.

C. Antacids can interfere with sucralfate by altering its pH-dependent activation and should not be taken simultaneously. If antacids are necessary for symptom relief, they should be taken at least 30 minutes before or after sucralfate.

D. There is no specific instruction to remain upright after taking sucralfate