A nurse is collecting data from an older adult client who is receiving ondansetron IV, has a history of diabetes mellitus and cardiac myopathy, and is receiving chemotherapy to treat cancer. For which of the following adverse effects of ondansetron should the nurse monitor? (Select all that apply)

B. One of the significant changes that occur with aging is a decline in kidney function. This includes a decrease in renal blood flow, glomerular filtration rate (GFR), and the ability of the kidneys to concentrate urine. These changes can impair the body's ability to conserve water and maintain electrolyte balance, increasing the risk of dehydration.

A. As individuals age, there is actually a decrease in the percentage of body water relative to lean body mass. This is because aging is associated with an increase in adipose tissue and a decrease in muscle mass, which affects the overall body composition.

C Saliva production typically decreases with age, rather than increases. Reduced saliva production can contribute to dry mouth and may affect hydration status indirectly, but it is not a primary factor in increasing dehydration risk in older adults.

D. While changes in blood pressure can occur with aging, such as an increase in systolic blood pressure due to arterial stiffening, this does not directly contribute to an increased risk of dehydration. Blood pressure changes are more related to cardiovascular health rather than fluid balance.

D. Administering the injection in the love handles, 2 inches from the umbilicus. It is important not to remove the air bubble from the prefilled syringe, as it is designed to ensure the entire dose of medication is administered.

A. Enoxaparin should not be transferred into another syringe unless specifically instructed by the manufacturer or pharmacy guidelines. Pre-filled syringes are designed to deliver the correct dose accurately and safely.

B. It is important not to remove the air bubble from the prefilled syringe, as it is designed to ensure the entire dose of medication is administered.

C. A 30-degree angle is too shallow for subcutaneous injections and may result in the medication being deposited too close to the skin surface, potentially causing irritation or affecting absorption.