A nurse is collecting data from a client who is taking levodopa-carbidopa to treat Parkinson's disease. Which of the following findings should the nurse document as an adverse effect of this medication?

A. Take the medication and then lay down for 30 min. Doxycycline can cause esophageal irritation and ulceration if not taken properly. Clients should remain upright for at least 30 minutes after taking the medication to reduce the risk of esophagitis. Lying down immediately after ingestion increases this risk.
B. Take the medication with an antacid. Antacids containing aluminum, calcium, or magnesium can interfere with doxycycline absorption, reducing its effectiveness. Clients should avoid taking antacids within 1 to 2 hours of doxycycline administration.
C. Take the medication with calcium-fortified orange juice. Calcium interferes with the absorption of doxycycline, potentially decreasing its effectiveness. Clients should avoid dairy products and calcium-rich foods or beverages when taking this medication.
D. Take the medication with crackers. Taking doxycycline with food, such as crackers or a light snack, can help reduce gastrointestinal discomfort without significantly affecting its absorption. Although doxycycline is best absorbed on an empty stomach, taking it with a small amount of food can help minimize nausea and vomiting.

A. Bradycardia is not a common adverse effect of levodopa-carbidopa. Instead, it may sometimes cause tachycardia (increased heart rate) in some patients. Monitoring for cardiovascular changes is essential, but bradycardia is not typically associated with this medication.
B. Hypotension is a documented adverse effect of levodopa-carbidopa. This medication can cause orthostatic hypotension, which is a drop in blood pressure when standing up, leading to dizziness or fainting. This finding should be carefully monitored and documented, as it can increase the risk of falls.
C. Constricted pupils are not typically an adverse effect of levodopa-carbidopa. Instead, this medication may cause dilated pupils (mydriasis) as a result of its effects on the autonomic nervous system, particularly if the patient is taking other medications that can affect pupil size.
D. Urinary frequency can occur with levodopa-carbidopa; however, it is not commonly classified as a significant adverse effect. While changes in urinary habits can happen, they are more often related to Parkinson's disease itself rather than the medication specifically. Therefore, urinary frequency should be monitored but is not a primary concern compared to hypotension.