A nurse is caring for a patient who is newly prescribed with celecoxib (Celebrex) Which of the following statements is TRUE regarding celecoxib (Celebrex)?

This medication inhibits CCX 2 receptors only

This medication inn bis mu and kappa receptors."

This medication inhibits kappa receptors only.

This medication inhibits du receptors only.

Answer and Explanation

The Correct Answer is A

A.   This medication inhibits COX-2 receptors only: Celecoxib is a selective COX-2 inhibitor used to reduce inflammation and pain.
B.   This medication inhibits mu and kappa receptors: Celecoxib does not affect opioid receptors.
C.   This medication inhibits kappa receptors only: Celecoxib does not target kappa receptors.
D.   This medication inhibits COX receptors only: Celecoxib specifically targets COX-2, not all cyclooxygenase receptors.

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Correct Answer is A

Explanation

A. The first-pass effect refers to the metabolism of a drug in the liver before it reaches systemic circulation. This primarily affects oral medications, as they are absorbed through the gastrointestinal tract and first pass through the liver.
B. Intravenous (IV) drugs bypass the first-pass effect as they are directly introduced into the bloodstream.
C. Intramuscular (IM) and D. Subcutaneous (SC) routes also bypass the first-pass effect since the drug enters the bloodstream without passing through the liver initially.

A. Used to treat motion sickness. B. Prevention of stress ulcers for at-risk clients experiencing acute events C. Used to only treat heartburn D. Used to only treat nausea and vomiting

Correct Answer is B

Explanation

A. Omeprazole is not used for motion sickness. It is a proton pump inhibitor used to treat gastric acid- related conditions.
B. Omeprazole is used to prevent and treat gastric ulcers, including stress ulcers that may occur in critically ill patients.
C. Omeprazole is used to treat conditions like GERD, ulcers, and Zollinger-Ellison syndrome, not just heartburn.
D. Omeprazole is not used to treat nausea and vomiting. It reduces gastric acid production to treat acid- related conditions.

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A nurse is caring for a patient who is newly prescribed with celecoxib (Celebrex) Which of the following statements is TRUE regarding celecoxib (Celebrex)?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following routes is affected by the first-pass effect?

Correct Answer is A

Explanation

A nurse is caring for a client that is newly prescribed with omeprazole (Prilosec). Which of the following options is a correct indication for omeprazole Prilosec)?

Correct Answer is B

Explanation

The client has been prescribed acetylsalicylic acid (Aspirin) by the healthcare provider. However, the client is not sure about the uses of aspirin. What of the following are the appropriate indications for aspirin? (Select All That Apply.).

A nurse is providing teaching to a female client who is taking conjugated equine estrogens (Premarin). Which of the following clients are contraindicated for conjugated equine estrogens (Premarin)? (Select All That Apply).

A nurse is providing information to a client who has a new prescription for hydrochlorothiazide (Hydro Diuril). Which of the following information should the nurse include?

A nurse is reviewing the phases of pharmacokinetics. Which of the following phases is the change of a drug into a less or more potent or more soluble form after it passes through the liver?

The nurse is educating a client about taking a tetracycline along with an antacid. The nurse explains to the client not to take these two medications because the antacid can reduce the absorption of the tetracycline. When one drug reduces the effect of another, it is:

A nurse is caring for a patient that is prescribed with a controlled substance. Which of the following statements accurately describes controlled substances?

The nurse is providing an in-service on mucosal protectants. What medication protects the ulcer from further injury from acid and pepsin and is a viscous substance that can stick to the ulcer for up to 6 hours?

A client is newly diagnosed with benign prostatic hyperplasia (BPH) Which of the following medications used to treat BPH? (Select All That Apply]