A nurse is caring for a client who is taking azathioprine to treat rheumatoid arthritis. Which of the following laboratory values indicates an adverse effect of this medication?

BUN 15 mg/dL

WBC 3,000/mm²

Het 45W

Platelets 250.000/mm²

Answer and Explanation

The Correct Answer is B

A. BUN 15 mg/dL (Blood Urea Nitrogen):
BUN is a measure of kidney function, and an elevated BUN may suggest impaired kidney function. However, it is not a specific marker for azathioprine adverse effects.
B. WBC 3,000/mm² (White Blood Cell count):
This is the correct answer. Azathioprine can suppress bone marrow function, leading to leukopenia (low white blood cell count). A WBC count of 3,000/mm² indicates a lower-than-normal white blood cell count, which can increase the risk of infection.
C. Hct 45% (Hematocrit):
Hematocrit measures the percentage of red blood cells in the blood. While it can be affected by various factors, it is not a specific marker for azathioprine adverse effects.
D. Platelets 250,000/mm²:
Platelets are involved in blood clotting, and a platelet count of 250,000/mm² is within the normal range. Azathioprine is not typically associated with adverse effects on platelet counts.

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Correct Answer is C

Explanation

A. Stroke volume: While stroke volume is an important parameter in assessing cardiac function, it may not directly guide the titration of nitroprusside infusion. Blood pressure is a more immediate indicator of the drug's effect on vasodilation.
B. Urine output: Nitroprusside primarily affects the vascular system and is not directly associated with urine output. Monitoring urine output is crucial in assessing renal function, but it is not the primary parameter for titrating a nitroprusside infusion.
C. Blood pressure (Correct Answer): Nitroprusside acts as a direct vasodilator, and its primary effect is on blood vessels, leading to a reduction in blood pressure. Therefore, monitoring blood pressure is essential to titrate the infusion to achieve the desired therapeutic effect.
D. Cardiac output: While nitroprusside's vasodilatory effect may influence cardiac output indirectly, blood pressure is a more immediate and specific parameter to guide the titration of the infusion. Nitroprusside is often titrated to reach a target blood pressure range in hypertensive emergencies.

A. Decrease in urine output B. Increase in serum glucose C. Increase in WBC count D. Decrease in blood pressure

Correct Answer is A

Explanation

A. Decrease in urine output:
This is the correct answer. Desmopressin is a synthetic form of antidiuretic hormone (ADH) that works to reduce urine output in individuals with diabetes insipidus. A decrease in urine output indicates a positive response to the medication.
B. Increase in serum glucose:
Desmopressin does not have a direct effect on serum glucose levels. Its primary action is to increase water reabsorption in the kidneys, reducing urine output.
C. Increase in WBC count:
Desmopressin does not have a direct impact on white blood cell (WBC) count. Its main action is on fluid balance and urine concentration.
D. Decrease in blood pressure:
Desmopressin can cause a mild increase in blood pressure, particularly at higher doses. However, blood pressure changes are not the primary therapeutic effect of desmopressin in the context of diabetes insipidus.

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A nurse is caring for a client who is taking azathioprine to treat rheumatoid arthritis. Which of the following laboratory values indicates an adverse effect of this medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is preparing to titrate a continuous nitroprusside infusion for a client. The nurse should plan to titrate the infusion according to which of the following assessments?

Correct Answer is C

Explanation

A nurse is caring for a client who has diabetes insipidus and is receiving desmopressin by intermittent IV balus. Which of the fediowing manifestations should indicate to the nurse a therapeutic response to the medication?

Correct Answer is A

Explanation

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