A nurse is caring for a client who is receiving a transfusion of packed red blood cells and develops itching and hives. What should be the nurse’s first response?

Choice A rationale:

Hypovolemic shock is a type of shock that occurs when there is a significant loss of blood or fluid volume, leading to decreased cardiac output and tissue perfusion. This can be caused by severe bleeding, dehydration, burns, or other conditions that result in fluid loss. While anaphylaxis can involve some fluid shifts, it is not primarily characterized by a loss of blood or fluid volume.

Key features of hypovolemic shock that distinguish it from anaphylactic shock include:

Prominent signs of dehydration: Dry skin and mucous membranes, decreased urine output, sunken eyes, and poor skin turgor.

Hemodynamic changes: Tachycardia, narrow pulse pressure, and cold extremities due to vasoconstriction to maintain blood pressure.

Laboratory findings: Elevated hematocrit and blood urea nitrogen (BUN) levels, indicating hemoconcentration and decreased kidney perfusion.

Choice B rationale:

Obstructive shock is a type of shock that occurs when there is an obstruction to blood flow, preventing adequate circulation to the body's tissues. This can be caused by conditions such as pulmonary embolism, cardiac tamponade, or tension pneumothorax. Anaphylaxis does not involve a physical obstruction to blood flow.

Key features of obstructive shock that distinguish it from anaphylactic shock include:

Evidence of the underlying obstruction: Jugular venous distension (cardiac tamponade), muffled heart sounds (cardiac tamponade), or respiratory distress (pulmonary embolism or tension pneumothorax).

Distinctive hemodynamic changes: Equalization of diastolic pressures between the right and left ventricles (cardiac tamponade).

Specific imaging findings: Enlarged cardiac silhouette on chest X-ray (pericardial effusion), filling defects in the pulmonary arteries on CT angiography (pulmonary embolism), or hyperexpanded lung fields with a deviated trachea on chest X-ray (tension pneumothorax).

Choice C rationale:

Cardiogenic shock is a type of shock that occurs when the heart is unable to pump enough blood to meet the body's needs. This can be caused by conditions such as heart attack, heart failure, or cardiomyopathy. Anaphylaxis does not primarily involve a failure of the heart's pumping function.

Key features of cardiogenic shock that distinguish it from anaphylactic shock include:

Evidence of heart failure: Pulmonary edema, elevated jugular venous pressure, and a third heart sound (S3 gallop).

Electrocardiogram (ECG) changes: ST-segment elevation or depression, Q waves, or other signs of myocardial ischemia or infarction.

Elevated cardiac enzymes: Troponin and creatine kinase-MB (CK-MB) levels, indicating heart muscle damage.

Rationale for Choice A: Obtain vital signs

While obtaining vital signs is important in assessing a patient's overall condition, it is not the first priority in a suspected transfusion reaction.

Vital signs can provide valuable information about the severity of the reaction, but they should not delay the immediate action of stopping the transfusion.

Delaying the cessation of the transfusion could allow for further infusion of incompatible blood or allergens, potentially worsening the reaction and leading to more serious complications.

Rationale for Choice B: Notify the registered nurse

Involving other healthcare professionals is crucial in managing transfusion reactions, but it should not precede stopping the transfusion.

The nurse should prioritize stopping the transfusion to prevent further exposure to potential triggers and then promptly notify the registered nurse for further assessment and interventions.

Timely communication with the registered nurse is essential for coordinating care and ensuring appropriate treatment measures are implemented.

Rationale for Choice C: Administer diphenhydramine

Diphenhydramine, an antihistamine, can be used to treat allergic reactions, but it should not be administered as the first response in this scenario.

The priority is to halt the infusion of the blood product that is potentially causing the reaction.

Administering diphenhydramine before stopping the transfusion could mask the symptoms of the reaction, making it more difficult to assess its severity and progression.

Rationale for Choice D: Stop the transfusion

This is the correct and most immediate action to take when a patient develops itching and hives during a blood transfusion.

These symptoms are indicative of a possible allergic or transfusion reaction, and stopping the transfusion is essential to prevent further complications.

It's critical to act quickly to minimize the amount of incompatible blood or allergens that enter the patient's circulation.

By stopping the transfusion, the nurse can potentially prevent the reaction from worsening and safeguard the patient's well- being.