A nurse is caring for a client who has a sulfonamide allergy. Which of the following medications should the nurse identify as contraindicated?
Famotidine
Aspirin
Metronidazole
Glyburide
The Correct Answer is D
A. Famotidine is an H2 receptor antagonist used to treat conditions like ulcers and gastroesophageal reflux disease (GERD). It does not contain sulfonamide and is generally safe for patients with sulfonamide allergies.
B. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) used for pain relief, fever reduction, and anti-inflammatory purposes. It does not contain sulfonamide and is not contraindicated for patients with sulfonamide allergies.
C. Metronidazole is an antibiotic used to treat various infections, including those of the gastrointestinal tract and the reproductive system. It does not contain sulfonamide and is safe for patients with sulfonamide allergies.
D. Glyburide is a sulfonylurea used to treat type 2 diabetes by increasing insulin production in the pancreas. It contains sulfonamide and can cause allergic reactions in patients with sulfonamide allergies, making it contraindicated.
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Related Questions
Correct Answer is C
Explanation
A. Valerian is an herbal supplement commonly used for its sedative effects. It does not have a significant interaction with warfarin and is not contraindicated for concurrent use.
B. Probiotics are generally safe to use with warfarin and do not have a significant impact on its anticoagulant effects. They are not contraindicated for concurrent use.
C. Ginkgo biloba is known to increase the risk of bleeding when taken with warfarin. It has antiplatelet effects that can enhance the anticoagulant effects of warfarin, leading to an increased risk of bleeding complications. Therefore, it is contraindicated for concurrent use with warfarin.
D. Coenzyme Q10 is structurally similar to vitamin K and can potentially reduce the effectiveness of warfarin. However, it is not as strongly contraindicated as ginkgo biloba, which has a more pronounced effect on bleeding risk.
Correct Answer is B
Explanation
A. PTT (partial thromboplastin time) is used to monitor heparin therapy, not warfarin. It measures the intrinsic pathway of coagulation.
B. PT (prothrombin time) is the correct test to review before administering warfarin. PT measures the extrinsic pathway of coagulation and is used to calculate the INR (International Normalized Ratio), which helps monitor and adjust warfarin dosage to ensure therapeutic levels and prevent complications.
C. Total iron-binding capacity is a measure of iron status and is not relevant to warfarin therapy.
D. WBC (white blood cell count) is important for assessing infection or immune status but is not directly related to monitoring warfarin therapy.
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