A nurse is assessing a client who has an oral temperature of 39 degrees Celsius. Which of the following findings should the nurse expect?

The first step in the inflammatory response is the recognition of harmful stimuli by pattern recognition receptors (PRRs) on the surfaces of various cells, including immune cells and non-immune cells. PRRs recognize specific patterns associated with pathogens, damage-associated molecular patterns (DAMPs), and pathogen-associated molecular patterns (PAMPs), among others. This recognition leads to the activation of signaling pathways that promote the recruitment and activation of immune cells and the release of inflammatory mediators, such as cytokines and chemokines.

Once the PRRs recognize the harmful stimuli, inflammatory cells are activated, including neutrophils, macrophages, and dendritic cells. These cells then release inflammatory markers, such as C-reactive protein, which promote the recruitment and activation of more immune cells and further amplify the inflammatory response. Inflammatory pathways are also triggered, leading to the production of various inflammatory mediators and the activation of transcription factors that regulate the expression of genes involved in the inflammatory response.

The nurse should expect to find an increased heart rate in a client with a fever. An elevated body temperature can cause an increase in metabolic rate, which can lead to an increase in heart rate. This is a normal physiological response to fever and helps the body to generate heat and fight off infection.