A newly admitted client has been prescribed sulfamethoxazole/trimethoprim. The nurse understands that this medication is contraindicated based on which lab result?

Serum fasting glucose 101 mg/dL

platelets 160,000 uL

Serum creatinine 2.5 mg/dL

Hemoglobin 13.6 g/dL

Answer and Explanation

The Correct Answer is C

A.   A serum fasting glucose level of 101 mg/dL indicates a mild elevation but is not significantly high enough to contraindicate the use of TMP-SMX. It does not directly relate to the medication’s safety.
B.   A platelet count of 160,000 µL is within normal limits (normal range is typically 150,000-450,000 µL). This result does not indicate any contraindication for using TMP-SMX.

C.   A serum creatinine level of 2.5 mg/dL indicates impaired kidney function (normal range is typically 0.6-1.2 mg/dL). TMP-SMX can be contraindicated in patients with significant renal impairment due to the potential for drug accumulation and toxicity, particularly affecting renal function.
D.   A hemoglobin level of 13.6 g/dL is within normal limits (normal range is approximately 13.5-17.5 g/dL for males and 12.0-15.5 g/dL for females). This result does not indicate a contraindication for using TMP- SMX.

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Correct Answer is B

Explanation

This is the correct time to draw the peak level. The peak level is the highest concentration of the drug in the blood, which typically occurs about 30 minutes to an hour after the end of the infusion.

A. Platelet count of 148,000 uL B. Prothrombin Time (PT) of 14 seconds C. Activated Partial Thromboplastin Time (aPTT) of 25 seconds D. D-dimer of 500 ng/mL

Correct Answer is D

Explanation

A. This is a normal platelet count and is not directly related to DVT.
B. This is a normal PT result and does not indicate a clotting disorder that would predispose the client to DVT.
C. This is a normal aPTT result and does not indicate a clotting disorder that would predispose the client to DVT.
D. D-dimer is a marker of blood clot breakdown. An elevated D-dimer level suggests the presence of a blood clot, making it the most concerning laboratory result in this case.

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A newly admitted client has been prescribed sulfamethoxazole/trimethoprim. The nurse understands that this medication is contraindicated based on which lab result?

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Naxlex Comprehensive Predictor Exams

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