A group of nurses are discussing the difference of an agonist verses an antagonist. Which of the following medications may the nurse select as an agonist?

A. Neuroleptic malignant syndrome: Causes fever, muscle rigidity, autonomic instability, and altered mental status-not dry mouth or blurry vision.

B. Teratogenicity: Refers to birth defects from medications taken during pregnancy.

C. Parkinson-like syndrome: Involves tremors, muscle rigidity, and bradykinesia-not dry mouth or blurry vision.

D. Anticholinergic effects: Symptoms of dry mouth, blurred vision, and urinary retention are classic signs of anticholinergic side effects caused by medications like antihistamines, tricyclic antidepressants, and some antipsychotics.

A. Distribution: Distribution refers to the movement of the drug from the bloodstream to tissues and organs. Poor circulation can impair drug distribution, leading to reduced effectiveness or toxic accumulation.

B. Excretion: Excretion is the elimination of drugs, primarily through the kidneys. While circulation plays a role, excretion is more directly affected by renal function.

C. Metabolism: Metabolism occurs primarily in the liver and is not the primary concern in a client with poor circulation.

D. Absorption: Absorption refers to how the drug enters the bloodstream, which is more dependent on the GI tract (oral meds) or injection site (IV, IM meds) rather than circulation.